Endemic of zoonotic sporotrichosis - Profile of cases in children

被引:26
作者
de Lima Barros, Monica Bastos [1 ]
Macedo Alves Costa, Debora Lucia [1 ]
Pacheco Schubach, Tania Maria [2 ]
Francesconi do Valle, Antonio Carlos [1 ]
Lorenzi, Noemi Pereira [3 ]
Teixeira, Jose Liporage [3 ]
de Oliveira Schubach, Armando [1 ]
机构
[1] Fundacao Oswaldo Cruz, Evandro Chagas Clin Res Inst, Infect Dis Serv, BR-21040900 Rio De Janeiro, Brazil
[2] Fundacao Oswaldo Cruz, Evandro Chagas Clin Res Inst, Zoonosis Serv, BR-21040900 Rio De Janeiro, Brazil
[3] Fundacao Oswaldo Cruz, Evandro Chagas Clin Res Inst, Clin Pharm, BR-21040900 Rio De Janeiro, Brazil
关键词
sporotrichosis; child; zoonosis; endemic; Brazil;
D O I
10.1097/INF.0b013e31815bf309
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background: Sporotrichosis in childhood is rare in most countries. Isolated cases and small outbreaks related to recreational activities or without identification of the transmission mechanism have been reported. Methods: Series of case reports. The isolation of Sporothrix schenckii from exudates or fragments of lesions obtained from the patients was used as the criterion of inclusion in the study. Results: A total of 81 cases of sporotrichosis in children younger than 15 years of age were diagnosed at the Evandro Chagas Research Institute, Fiocruz, Brazil, between 1998 and 2004. These cases are part of the endemic disease occurring in Rio de Janeiro related to contact with domestic cats. There was a predominance of girls in the 10-14 year age group. The most frequent clinical form was the cutaneouslymphatic form located on the upper limbs. Itraconazole was used as the first-choice treatment. Sixty-six patients were cured, 9 were lost to follow-up, and 6 had spontaneous regression of the lesions. Conclusions: This is the largest series of childhood sporotrichosis with zoonotic transmission. The clinical presentation of sporotrichosis in children followed the same pattern of the disease in adults in this ongoing endemic.
引用
收藏
页码:246 / 250
页数:5
相关论文
共 21 条
  • [1] Positive Montenegro skin test among patients with sporotrichosis in Rio De Janeiro
    Barros, MBD
    Schubach, A
    Francesconi-do-Valle, AC
    Gutierrez-Galhardo, MC
    Schubach, TMP
    Conceiçao-Silva, F
    Salgueiro, MD
    Mouta-Confort, E
    Reis, RS
    Madeira, MD
    Cuzzi, T
    Quintella, LP
    Passos, JPD
    Conceiçao, MJ
    Marzochi, MCD
    [J]. ACTA TROPICA, 2005, 93 (01) : 41 - 47
  • [2] Barros MBD, 2004, CLIN INFECT DIS, V38, P529, DOI 10.1086/381200
  • [3] Unsuspected sporotrichosis in childhood
    Burch, JM
    Morelli, JG
    Weston, WL
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (04) : 442 - 445
  • [4] Endemic sporotrichosis
    Bustamante, B
    Campos, PE
    [J]. CURRENT OPINION IN INFECTIOUS DISEASES, 2001, 14 (02) : 145 - 149
  • [5] Epidemiology of sporotrichosis: A study of 304 cases in Brazil
    da Rosa, ACM
    Scroferneker, ML
    Vettorato, R
    Gervini, RL
    Vettorato, G
    Weber, A
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2005, 52 (03) : 451 - 459
  • [6] SPOROTRICHOSIS IN CHILDREN - REPORT OF AN EPIDEMIC
    DAHL, BA
    SILBERFARB, PM
    SAROSI, GA
    WEEKS, RJ
    TOSH, FE
    [J]. JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1971, 215 (12) : 1980 - +
  • [7] DONADEL K, 1992, ANAIS BRASILEIROS DE, V67, P121
  • [8] Galhardo MCG, 2002, INT J DERMATOL, V41, P114, DOI 10.1046/j.1365-4362.2002.01381_2.x
  • [9] Refractory subcutaneous abscesses caused by Sporothrix Schenckii. A new pathogenic fungus.
    Hektoen, L
    Perkins, CF
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1900, 5 (01) : 77 - U2
  • [10] STATISTICAL-SURVEY OF 150 CASES WITH SPOROTRICHOSIS
    KUSUHARA, M
    HACHISUKA, H
    SASAI, Y
    [J]. MYCOPATHOLOGIA, 1988, 102 (02) : 129 - 133