Current developments in endovascular therapy of peripheral vascular disease

被引:41
作者
Kokkinidis, Damianos G. [1 ]
Armstrong, Ehrin J. [1 ]
机构
[1] Univ Colorado, Div Cardiol, Rocky Mt Reg VA Med Ctr, Aurora, CO USA
关键词
peripheral artery disease; femoropopliteal disease; infrapopliteal disease; below the knee arteries; chronic total occlusions (CTOs); emerging therapies; novel technologies; adventitial delivery; lithotripsy; drug-eluting stents (DES); drug-coated balloons (DCBs); percutaneous bypass; IN-STENT RESTENOSIS; PACLITAXEL-COATED BALLOON; CRITICAL LIMB ISCHEMIA; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; SUPERFICIAL FEMORAL-ARTERY; PROXIMAL POPLITEAL ARTERIES; DRUG-ELUTING BALLOONS; BARE-METAL STENTS; FEMOROPOPLITEAL ARTERY; INFRAPOPLITEAL ARTERIES;
D O I
10.21037/jtd.2019.12.130
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
More than 200 million people worldwide have peripheral artery disease (PAD) or its most severe manifestation, critical limb ischemia (CLI). While endovascular treatment has become first line therapy in most cases, a number of challenges remain for optimal treatment of femoropopliteal (FP) or infrapopliteal (IP) disease, especially when these lesions are severely calcified, chronic total occlusions (CTOs) or instent restenosis (ISR). Continued evolution of technologies has significantly improved the outcomes for endovascular treatment. A number of new devices are in the pipeline right now, including new paclitaxel eluting stents and balloons, intravascular lithotripsy to treat severely calcified lesions, adventitial delivery of anti-restenotic agents to limit restenosis rates, and percutaneous femoro-popliteal bypass.
引用
收藏
页码:1681 / 1694
页数:14
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