One-pot solvent-free synthesis of pyranonaphthoquinonc-fused spirooxindoles catalyzed by SBA-IL

In this research, ionic liquid modified SBA-15 mesoporous material (SBA-IL) as a recyclable, heterogeneous catalyst efficiently catalyzed the synthesis of pyranonaphthoquinone-fused spirooxindoles through the one-pot three-component reaction of isatin derivatives, activated methylene reagents, and 2-hydroxy-1,4-naphthoquinone. The reactions were performed under microwave irradiation and solvent-free conditions. The synthesized SBA-IL was characterized by SEM, FT-IR, nitrogen adsorption-desorption, and thermogravimetric analyses. Excellent chemical yield, short reaction time, mild reaction condition, easy workup procedures, and reusability of catalyst are noteworthy advantages of this protocol. (C) 2018 Sharif University of Technology. All rights reserved.