Synthesis and Characterization of Biodegradable Poly(lactic-co-glycolic acid)

被引：6

作者：

Mei, Fangfang ^{[1
]}

Peng, Ya ^{[1
,2
]}

Lu, Shoutao ^{[1
]}

Sun, Fei ^{[1
]}

Zhang, Ying ^{[2
]}

Ge, Cui ^{[2
]}

Zhang, Yong ^{[2
]}

Gu, Hualin ^{[2
]}

Wang, Yangdan ^{[2
]}

Zhao, Xinwei ^{[3
]}

Wang, Guoyao ^{[2
]}

机构：

[1] XiHua Univ, Ctr Mat & Energy, Chengdu 610039, Peoples R China

[2] XiHua Univ, Sch Mat Sci & Engn, Chengdu 610039, Peoples R China

[3] Tokyo Univ Sci, Dept Phys, Tokyo 162, Japan

来源：

Journal of Macromolecular Science Part B-Physics | 2015年 / 54卷 / 05期

基金：

芬兰科学院;

关键词：

biodegradable; biomaterial; hydrophilicity; poly(lactic-co-glycolic acid); DEGRADATION; BLENDS;

D O I：

10.1080/00222348.2014.1002325

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A series of poly(lactic-co-glycolic acid) (PLGA) was synthesized by bulk ring-opening copolymerization with different ratios of L-lactic acid (L-LA) to glycolic acid (GA); stannous octoate [Sn(Oct)2] was used as catalyst. The structures were characterized by FT-IR. The crystallinity and the glass-transition temperature (T-g) were studied by differential scanning calorimeter (DSC). T-g decreased with the increase of GA and the rate of degradation and degree of hydrophilicity increased with the increased content of GA.

引用

页码：562 / 570

页数：9

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