Evolution of technology in replacement of heart valves: Transcatheter aortic valves, a revolution for management of valvular heart diseases

被引:10
作者
Coccia, Mario [1 ]
机构
[1] CNR Natl Res Council Italy, Coll Carlo Alberto, Via Real Coll, I-3010024 Turin, Italy
关键词
Transcatheter aortic valve implantation; Surgical aortic valve replacement; TAVI; SAVR; Aortic stenosis; Medical technology; Radical innovation; Evolution of technology; Technological evolution; Technology change; Innovation management; Health policy; COST-EFFECTIVENESS; IMPLANTATION; STENOSIS; OUTCOMES; PERFORMANCE; INNOVATION; TAVI;
D O I
10.1016/j.hlpt.2021.100512
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Objectives: The goal of this study is to analyze the evolution of technology in artificial heart valves for solving the problem of aortic stenosis (a narrowing of the aortic valve opening) that is one of the most common valvular heart diseases in society. In particular, this study explains the evolution of new technology of transcatheter aortic valve implantation (TAVI) compared to surgical aortic valve replacement (SAVR). Methods: Data of Scopus (2020) based scientific products and patents that have in title, abstract or keywords the following terms: "transcatheter aortic valve implantation (TAVI)" or "surgical aortic valve replacement (SAVR)". The evolution of technology is analyzed with a model, which shows how TAVI technique is substituting established technique of SAVR in cardiology. The relationships are investigated with loglinear models using ordinary least squares method for estimating the unknown parameters. Statistical analyses are performed with the Statistics Software SPSS (R) 26. Results: Statistical analyses reveal that TAVI, with its growing scientific and technological production, is expected to be a dominant technology in future for the treatment of aortic stenosis in society. In fact, the scientific production of TAVI has a coefficient of growth in function of time equal to 0.39(P<.001) compared to a coefficient for SAVR that is 0.10(P<.001). Statistical analyses with patent production confirm these results. Findings hint at general properties of the evolutionary behavior of this medical technology: 1) TAVI has a disproportionate growth in scientific products and patents compared to SAVR; 2) TAVI has a growing scientific and technological production driven by major and minor technological advances to solve consequential problems to treat valvular heart diseases; 3) learning via diffusion and diffusion by learning are driving forces underlying the development and adoption of TAVI in cardiology. Conclusions: TAVI, introduced in 2002, is growing in terms of scientific production and innovative activity to revolutionize the management of aortic stenosis in cardiology with important implications of health management based on improved cost-effectiveness of this new technology and better efficiency in healthcare of people.
引用
收藏
页数:9
相关论文
共 50 条
[41]   The Development of Transcatheter Heart Valves: Opportunities and Challenges [J].
Laske, Tim ;
Denton, Melissa ;
Eberhardt, Carol .
2009 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-20, 2009, :163-+
[42]   A series of four transcatheter aortic valve replacement in failed Perceval valves [J].
Misfeld, Martin ;
Abdel-Wahab, Mohamed ;
Thiele, Holger ;
Borger, Michael A. ;
Holzhey, David .
ANNALS OF CARDIOTHORACIC SURGERY, 2020, 9 (04) :280-288
[43]   Comparison of balloon-expandable valves versus self-expandable valves in high-risk patients undergoing transcatheter aortic valve replacement for severe aortic stenosis [J].
Chang, Hsiao-Huang ;
Chen, I-Ming ;
Chen, Po-Lin ;
Hsu, Tsui-Lieh ;
Lin, Su-Man ;
Chen, Ying-Hwa .
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2015, 78 (06) :331-338
[44]   Design of a Supporting Structure at the Aortic Annular Level for Anchoring of the Transcatheter Heart Valves [J].
Chan, Cody Leeheng ;
Yin, Wei-Hsian ;
Lee, Rueiling .
2024 11TH INTERNATIONAL CONFERENCE ON BIOMEDICAL AND BIOINFORMATICS ENGINEERING, ICBBE 2024, 2024, :211-218
[45]   Therapy of Aortic Valve Stenosis Using Next Generation Transcatheter Heart Valves [J].
Schaefer, A. ;
Conradi, L. ;
Schaefer, U. .
AKTUELLE KARDIOLOGIE, 2016, 5 (01) :52-58
[46]   Mechanically expanding transcatheter aortic valves: pros and cons of a unique device technology [J].
Yalta, Kenan ;
Gurdogan, Muhammet ;
Zorkun, Cafer ;
Gurlertop, Yekta .
CARDIOVASCULAR DIAGNOSIS AND THERAPY, 2018, 8 (04) :538-542
[47]   Transcatheter Aortic Valve Replacement for Degenerated Transcatheter Aortic Valves The TRANSIT International Project [J].
Testa, Luca ;
Agnifili, Mauro ;
Van Mieghem, Nicolas M. ;
Tchetche, Didier ;
Asgar, Anita W. ;
De Backer, Ole ;
Latib, Azeem ;
Reimers, Bernhard ;
Stefanini, Giulio ;
Trani, Carlo ;
Colombo, Antonio ;
Giannini, Francesco ;
Bartorelli, Antonio ;
Wojakowski, Wojtek ;
Dabrowski, Maciej ;
Jagielak, Dariusz ;
Banning, Adrian P. ;
Kharbanda, Rajesh ;
Moreno, Raul ;
Schofer, Joachim ;
van Royen, Niels ;
Pinto, Duane ;
Serra, Antoni ;
Segev, Amit ;
Giordano, Arturo ;
Brambilla, Nedy ;
Popolo Rubbio, Antonio ;
Casenghi, Matteo ;
Oreglia, Jacopo ;
De Marco, Federico ;
Tanja, Rudolph ;
McCabe, James M. ;
Abizaid, Alexander ;
Voskuil, Michiel ;
Teles, Rui ;
Biondi Zoccai, Giuseppe ;
Bianchi, Giovanni ;
Sondergaard, Lars ;
Bedogni, Francesco .
CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2021, 14 (06) :628-638
[48]   Impact of device-host interaction on paravalvular aortic regurgitation with different transcatheter heart valves [J].
Rodriguez-Olivares, Ramon ;
El Faquir, Nahid ;
Rahhab, Zouhair ;
van Gils, Lennart ;
Ren, Ben ;
Sakhi, Rafi ;
Geleijnse, Marcel L. ;
van Domburg, Ron ;
de Jaegere, Peter P. T. ;
Zamorano Gomez, Jose L. ;
Van Mieghem, Nicolas M. .
CARDIOVASCULAR REVASCULARIZATION MEDICINE, 2019, 20 (02) :126-132
[49]   Transcatheter aortic valve implantation in patients with a small aortic annulus: performance of supra-, intra- and infra-annular transcatheter heart valves [J].
Voigtlaender, Lisa ;
Kim, Won-Keun ;
Mauri, Victor ;
Gossling, Alina ;
Renker, Matthias ;
Sugiura, Atsushi ;
Linder, Matthias ;
Schmidt, Tobias ;
Schofer, Niklas ;
Westermann, Dirk ;
Reichenspurner, Hermann ;
Nickenig, Georg ;
Blankenberg, Stefan ;
Hamm, Christian ;
Conradi, Lenard ;
Adam, Matti ;
Sinning, Jan-Malte ;
Seiffert, Moritz .
CLINICAL RESEARCH IN CARDIOLOGY, 2021, 110 (12) :1957-1966
[50]   Efficacy and safety of new-generation transcatheter aortic valves: insights from the Israeli transcatheter aortic valve replacement registry [J].
Finkelstein, Ariel ;
Steinvil, Arie ;
Rozenbaum, Zach ;
Halkin, Amir ;
Banai, Shmuel ;
Barbash, Israel ;
Guetta, Victor ;
Segev, Amit ;
Danenberg, Haim ;
Orvin, Katia ;
Assa, Hana Vaknin ;
Assali, Abid ;
Kornowski, Ran .
CLINICAL RESEARCH IN CARDIOLOGY, 2019, 108 (04) :430-437