Preventing kidney cell suicide

被引:19
作者
Brownlee, Michael [1 ]
机构
[1] Albert Einstein Coll Med, Juvenile Diabet Res Fdn, Int Ctr Diabet Complicat Res, Bronx, NY 10461 USA
关键词
D O I
10.1038/nm1107-1284
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Decreased levels of activated protein C allow for kidney cell death in a mouse model of diabetic nephropathy. The findings suggest that targeting the antiapoptotic protein C pathway could counteract kidney damage in individuals with diabetes (pages 1349–1358).
引用
收藏
页码:1284 / 1285
页数:3
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