Preoperative chemoradiotherapy in rectal cancer experience in 76 patients

被引：0

作者：

Bannura C, Guillermo ^{[1
,2
]}

Barrera E, Alejandro ^{[1
,2
]}

Melo L, Carlos ^{[1
,2
]}

Contreras P, Jaime ^{[1
,2
]}

Soto C, Daniel ^{[1
,2
]}

机构：

[1] Univ Chile, Hosp Clin San Borja Arriaran, Fac Med, Campus Ctr,Serv Cirugia, Santiago, Chile

[2] Univ Chile, Hosp Clin San Borja Arriaran, Fac Med, Campus Ctr,Dept Cirugia, Santiago, Chile

来源：

REVISTA CHILENA DE CIRUGIA | 2010年 / 62卷 / 06期

关键词：

Rectal cancer; chemotherapy; radiotherapy; NEOADJUVANT CHEMORADIATION; TUMOR RESPONSE; RADIATION; RADIOCHEMOTHERAPY; RADIOTHERAPY; CARCINOMA; STAGE;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background Preoperative chemoradiotherapy is helpful as an adjuvant treatment for locally advanced rectal carcinoma Aim To report the results of a prospective series of patients with rectal carcinoma treated with chemoradiotherapy and surgical excision Material and Methods Seventy six patients aged 28 to 84 years (51% women), with locally advanced rectal cancer (T3-T4 or N+) subjected to curative surgery and treated with radiotherapy and 5 fluoruracil with leucovorin, were included in this series Results Mean hospital stay was 12 5 +/- 7 2 days, 37% had Operative complications and no patient died The downstaging effect was more marked for local invasion than for lymph node involvement In 21% of cases, a complete pathological response was achieved and no patient has had a relapse during a 59 months follow up Conclusions Among patients with rectal cancer, preoperative chemoradiotherapy does not increase surgical complications and has a marked impact in tumor downstaging

引用

页码：607 / 613

页数：7

共 28 条

[1] Mortality and morbidity after surgery of mid and low rectal cancer - Results of a French prospective multicentric study [J].