Efficiency and safety of recombinant activated factor VII in a case of severe postpartum hemorrhage

被引：5

作者：

Geiger, A. ^{[1
]}

Collange, O. ^{[1
]}

Samin, J. ^{[1
]}

Meyer, A. ^{[1
]}

Freys, G. ^{[1
]}

Pottecher, T. ^{[1
]}

机构：

[1] Hop Hautepierre, Serv Anesthesie Reanimat, F-67098 Strasbourg, France

来源：

ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION | 2010年 / 29卷 / 10期

关键词：

Recombinant activated factor VII; Postpartum hemorrhage; Risk-benefit ratio; MASSIVE OBSTETRIC HEMORRHAGE; THERAPY;

D O I：

10.1016/j.annfar.2010.05.004

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We report the case of a severe postpartum hemorrhage (PPH) that was successfully treated with two administrations of recombinant activated factor VII (rFVIIa). Two major thromboembolic events (TEE) occurred shortly afterwards: the first was an acute lower limb ischemia at H3, the second was a cardiac arrest complicating a massive pulmonary embolism on day 5. Fortunately, both events had a favorable outcome. This case report allows us to discuss the role of rFVIIa during severe PPH and its potential responsibility in these two major TEE. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：728 / 731

页数：4

共 21 条

[1] An open non-randomized study of recombinant activated factor VII in major postpartum haemorrhage [J].

Ahonen, J. ;

Jokela, R. ;

Korttila, K. .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2007, 51 (07) :929-936

[2] Recombinant factor VIIa for life-threatening post-partum haemorrhage [J].

Ahonen, J ;

Jokela, R .

BRITISH JOURNAL OF ANAESTHESIA, 2005, 94 (05) :592-595

[3] Use of recombinant activated factor VII in primary postpartum hemorrhage -: The northern European registry 2000-2004 [J].

Alfirevic, Zarko ;

Elbourne, Diana ;

Pavord, Sue ;

Bolte, Antoinette ;

Van Geijn, Herman ;

Mercier, Frederic ;

Ahonen, Jouni ;

Bremme, Katarina ;

Bodker, Birgit ;

Magnusdottir, Ebba Margret ;

Salvesen, Kjell ;

Prendiville, Walter ;

Truesdale, Ann ;

Clemens, Felicity ;

Piercy, Deborah ;

Gyte, Gill .

OBSTETRICS AND GYNECOLOGY, 2007, 110 (06) :1270-1278

[4]

Boyer-Neumann C, 2005, EMC HEMATOLOGIE, V2, P132

[5]

Boyer-Neumann C, 2006, REANIMATION, V15, P576

[6] Recombinant activated factor VII as a life-saving therapy for severe postpartum haemorrhage unresponsive to conservative traditional management [J].

Brice, A ;

Hilbert, U ;

Roger-Christoph, S ;

Fernandez, H ;

Dumenil, AS ;

Descorps-Declère, A ;

Mercier, F ;

Benhamou, D .

ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION, 2004, 23 (11) :1084-1088

[7]

*COMM AUT MIS MARC, REF BON US

[8] Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy:: a double-blind placebo-controlled andomised trial [J].

Friederich, PW ;

Herny, CP ;

Messelink, EJ ;

Geerdink, MG ;

Keller, T ;

Kurth, KH ;

Büller, HR ;

Levi, M .

LANCET, 2003, 361 (9353) :201-205

[9] Use of recombinant activated factor VII in massive obstetric haemorrhage [J].

Haynes, J. ;

Laffan, M. ;

Plaat, F. .

INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA, 2007, 16 (01) :40-49

[10]

*I VEILL SAN, B EP HEBD MORT MAT F

← 1 2 3 →