Complete Nucleotide Sequence of KPC-3-Encoding Plasmid pKpQIL in the Epidemic Klebsiella pneumoniae Sequence Type 258

被引：109

作者：

Leavitt, Azita ^{[1
]}

Chmelnitsky, Inna ^{[1
]}

Carmeli, Yehuda ^{[1
]}

Navon-Venezia, Shiri ^{[1
]}

机构：

[1] Tel Aviv Univ, Sackler Fac Med, Tel Aviv Sourasky Med Ctr, Mol Epidemiol & Antibiot Resistance Lab,Div Epide, IL-64239 Tel Aviv, Israel

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 10期

关键词：

BETA-LACTAMASE KPC-2; UNITED-STATES; CARBAPENEMASE; RESISTANCE; ENTEROBACTERIACEAE; EMERGENCE; STRAINS; ISOLATE; THREAT; TEM-1;

D O I：

10.1128/AAC.00175-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have determined the entire DNA sequence of plasmid pKpQIL, the bla(KPC-3)-carrying plasmid harbored by the carbapenem-resistant Klebsiella pneumoniae clone sequence type 258 (ST 258) in Israel. pKpQIL is a 113,637-bp, self-transmissible plasmid that belongs to the incompatibility group IncFII. It consists of a large backbone of a pKPN4-like plasmid and carries the bla(KPC-3)-containing Tn4401a transposon of a pNYC-like plasmid.

引用

页码：4493 / 4496

页数：4

共 21 条

[1] Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing β-lactamase KPC-2 in intensive care units of a Chinese hospital [J].

Cai, Jia Chang ;

Zhou, Hong Wei ;

Zhang, Rong ;

Chen, Gong-Xiang .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (06) :2014-2018

[2] Identification of plasmids by PCR-based replicon typing [J].

Carattoli, A ;

Bertini, A ;

Villa, L ;

Falbo, V ;

Hopkins, KL ;

Threlfall, EJ .

JOURNAL OF MICROBIOLOGICAL METHODS, 2005, 63 (03) :219-228

[3] Resistance Plasmid Families in Enterobacteriaceae [J].

Carattoli, Alessandra .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (06) :2227-2238

[4] Plasmid-mediated carbapenem-hydrolyzing β-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece [J].

Cuzon, Gaelle ;

Naas, Thierry ;

Demachy, Marie Claude ;

Nordmann, Patrice .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (02) :796-797

[5] Intercontinental travels of patients and dissemination of plasmid-mediated carbapenemase KPC-3 associated with OXA-9 and TEM-1 [J].

Dortet, Laurent ;

Radu, Irina ;

Gautier, Valerie ;

Blot, Francois ;

Chachaty, Elisabeth ;

Arlet, Guillaume .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (02) :455-457

[6] Genetic Organization of Transposase Regions Surrounding blaKPC Carbapenemase Genes on Plasmids from Klebsiella Strains Isolated in a New York City Hospital [J].

Gootz, Thomas D. ;

Lescoe, Mary Kay ;

Dib-Hajj, Fadia ;

Dougherty, Brian A. ;

He, Wen ;

Della-Latta, Phyllis ;

Huard, Richard C. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (05) :1998-2004

[7] Molecular Epidemiology of KPC-Producing Klebsiella pneumoniae Isolates in the United States: Clonal Expansion of Multilocus Sequence Type 258 [J].

Kitchel, Brandon ;

Rasheed, J. Kamile ;

Patel, Jean B. ;

Srinivasan, Arjun ;

Navon-Venezia, Shiri ;

Carmeli, Yehuda ;

Brolund, Alma ;

Giske, Christian G. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (08) :3365-3370

[8] Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital [J].

Leavitt, Azita ;

Navon-Venezia, Shiri ;

Chmelnitsky, Inna ;

Schwaber, Mitchell J. ;

Carmeli, Yehuda .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (08) :3026-3029

[9] Plasmid pKpQIL encoding KPC-3 and TEM-1 confers carbapenem resistance in an extremely drug-resistant epidemic Klebsiella pneumoniae strain [J].

Leavitt, Azita ;

Chmelnitsky, Inna ;

Ofek, Itzhak ;

Carmeli, Yehuda ;

Navon-Venezia, Shiri .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2010, 65 (02) :243-248

[10] Genome sequencing in microfabricated high-density picolitre reactors [J].

Margulies, M ;

Egholm, M ;

Altman, WE ;

Attiya, S ;

Bader, JS ;

Bemben, LA ;

Berka, J ;

Braverman, MS ;

Chen, YJ ;

Chen, ZT ;

Dewell, SB ;

Du, L ;

Fierro, JM ;

Gomes, XV ;

Godwin, BC ;

He, W ;

Helgesen, S ;

Ho, CH ;

Irzyk, GP ;

Jando, SC ;

Alenquer, MLI ;

Jarvie, TP ;

Jirage, KB ;

Kim, JB ;

Knight, JR ;

Lanza, JR ;

Leamon, JH ;

Lefkowitz, SM ;

Lei, M ;

Li, J ;

Lohman, KL ;

Lu, H ;

Makhijani, VB ;

McDade, KE ;

McKenna, MP ;

Myers, EW ;

Nickerson, E ;

Nobile, JR ;

Plant, R ;

Puc, BP ;

Ronan, MT ;

Roth, GT ;

Sarkis, GJ ;

Simons, JF ;

Simpson, JW ;

Srinivasan, M ;

Tartaro, KR ;

Tomasz, A ;

Vogt, KA ;

Volkmer, GA .

NATURE, 2005, 437 (7057) :376-380

← 1 2 3 →