Cobalt and Chromium Ion Release After Large-Diameter Metal-on-Metal Total Hip Arthroplasty

被引：54

作者：

Hasegawa, Masahiro ^{[1
]}

Yoshida, Kakunoshin ^{[1
]}

Wakabayashi, Hiroki ^{[1
]}

Sudo, Akihiro ^{[1
]}

机构：

[1] Mie Univ, Grad Sch Med, Dept Orthopaed Surg, Tsu, Mie 5148507, Japan

来源：

JOURNAL OF ARTHROPLASTY | 2012年 / 27卷 / 06期

关键词：

total hip arthroplasty; metal on metal; metal ion; lymphocyte; pseudotumor; RESURFACING ARTHROPLASTY; WEAR; REPLACEMENT; FAILURE; BLOOD; CORROSION; SIMULATOR; BEARINGS; JOINTS; SERUM;

D O I：

10.1016/j.arth.2011.12.016

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Seventy-five patients underwent unilateral metal-on-metal total hip arthroplasty using a large-diameter head. Serum levels of cobalt and chromium were determined. Significant increases in both cobalt and chromium were observed at 3 months (cobalt, 1.4 mu g/L; chromium, 1.4 mu g/L) compared with preoperative values (P < .001). At 1 year, the median cobalt and chromium levels were 2.3 and 2.1 mu g/L, respectively, and the levels had increased significantly compared with 3 months (P < .001). There were no significant differences between levels of either metal at 1 or 2 years (cobalt, 2.3 mu g/L; chromium, 1.6 mu g/L). Pseudotumor occurred in 2 hips. Patients with large-diameter metal-on-metal total hip arthroplasty had higher circulating metal ion levels at 3 months and 1 year, with no additional significant increases at 2 years.

引用

页码：990 / 996

页数：7

共 45 条

[1]

Allan D Gordon, 2007, J Surg Orthop Adv, V16, P12

[2] Metal ion levels in the blood of patients after hip resurfacing: A comparison between twenty-eight and thirty-six-millimeter-head metal-on-metal prostheses [J].