Mechanical ventilation in pediatric intensive care units during the season for acute lower respiratory infection: A multicenter study

被引：49

作者：

Farias, Julio A. ^{[1
]}

Fernandez, Analia ^{[1
]}

Monteverde, Ezequiel ^{[1
]}

Flores, Juan C. ^{[2
]}

Baltodano, Aristides ^{[3
]}

Menchaca, Amanda ^{[4
]}

Poterala, Rossana ^{[1
]}

Panico, Flavia ^{[5
]}

Johnson, Maria ^{[6
]}

von Dessauer, Bettina ^{[7
]}

Donoso, Alejandro ^{[8
]}

Zavala, Ines ^{[9
]}

Zavala, Cesar ^{[10
]}

Troster, Eduardo ^{[5
]}

Pena, Yolanda ^{[11
]}

Flamenco, Carlos

Almeida, Helena ^{[12
]}

Nilda, Vidal ^{[13
]}

Esteban, Andres ^{[14
,15
]}

机构：

[1] Hosp Ninos Dr Ricardo Gutierrez, Caba, Argentina

[2] Hosp Ninos Jesus, Madrid, Spain

[3] Hosp Nacl Ninos Dr Carlos Saenz Herrera, San Jose, Costa Rica

[4] Hosp Ninos Pereyra Rossel, Montevideo, Uruguay

[5] Inst Crianca Prof P de Alcantara HCFMUSP, Sao Paulo, Brazil

[6] Hosp Ninos Panama, Panama City, Panama

[7] Hosp Ninos Roberto Del Rio, Santiago, Chile

[8] Hosp Padre Hurtado, Santiago, Chile

[9] Hosp Ninos R Gilbert, Guayaquil, Ecuador

[10] Hosp Especialidades Ctr Med La Raza, IHSS, Tegucigalpa, Honduras

[11] Hosp Materno Infantil Vall Dhebron, Barcelona, Spain

[12] Hosp Fernando Fonseca, Lisbon, Portugal

[13] Hosp Prof A Posadas, Buenos Aires, DF, Argentina

[14] Hosp Univ Getafe, Madrid, Spain

[15] CIBER Enfermedades Resp, Madrid, Spain

来源：

PEDIATRIC CRITICAL CARE MEDICINE | 2012年 / 13卷 / 02期

关键词：

acute lower respiratory infection; children; infants; mechanical ventilation; modes; survey; weaning outcomes; ACUTE LUNG INJURY; QUALITY IMPROVEMENT; EXTUBATION SUCCESS; CHILDREN; INFANTS; FEASIBILITY; PREDICTORS; PRESSURE; OUTCOMES; FAILURE;

D O I：

10.1097/PCC.0b013e3182257b82

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: To describe the characteristics and outcomes of mechanical ventilation in pediatric intensive care units during the season of acute lower respiratory infections. Design: Prospective cohort of infants and children receiving mechanical ventilation for at least 12 hrs. Setting: Sixty medical-surgical pediatric intensive care units. Patients: All consecutive patients admitted to participating pediatric intensive care units during a 28-day period. Measurements and Main Results: Of 2,156 patients admitted to pediatric intensive care units, 1185 (55%) received mechanical ventilation for a median of 5 days (interquartile range 2-8). Median age was 7 months (interquartile range 2-25). Main indications for mechanical ventilation were acute respiratory failure in 78% of the patients, altered mental status in 15%, and acute on chronic pulmonary disease in 6%. Median length of stay in the pediatric intensive care units was 10 days (interquartile range 6-18). Overall mortality rate in pediatric intensive care units was 13% (95% confidence interval: 11-15) for the entire population, and 39% (95% confidence interval: 23-58) in patients with acute respiratory distress syndrome. Of 1150 attempts at liberation from mechanical ventilation, 62% (95% confidence interval: 60-65) used the spontaneous breathing trial, and 37% (95% confidence interval: 35-40) used gradual reduction of ventilatory support. Noninvasive mechanical ventilation was used initially in 173 patients (15%, 95% confidence interval: 13-17). Conclusion: In the season of acute lower respiratory infections, one of every two children admitted to pediatric intensive care units requires mechanical ventilation. Acute respiratory failure was the most common reason for mechanical ventilation. The spontaneous breathing trial was the most commonly used method for liberation from mechanical ventilation. (Pediatr Crit Care Med 2012; 13: 158-164)

引用

页码：158 / 164

页数：7

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