The iceLogo web server and SOAP service for determining protein consensus sequences

被引：41
|
作者：
Maddelein, Davy [1 ,2 ]
Colaert, Niklaas [1 ,2 ]
Buchanan, Iain [1 ,2 ]
Hulstaert, Niels [1 ,2 ]
Gevaert, Kris [1 ,2 ]
Martens, Lennart [1 ,2 ]
机构：
[1] Univ Ghent VIB, Dept Med Prot Res, B-9000 Ghent, Belgium
[2] Univ Ghent, Fac Med & Hlth Sci, Dept Biochem, B-9000 Ghent, Belgium
来源：
NUCLEIC ACIDS RESEARCH | 2015年 / 43卷 / W1期
关键词：
VISUALIZATION; LOGOS; TOOL;
D O I：
10.1093/nar/gkv385
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The iceLogo web server and SOAP service implement the previously published iceLogo algorithm. iceLogo builds on probability theory to visualize protein consensus sequences in a format resembling sequence logos. Peptide sequences are compared against a reference sequence set that can be tailored to the studied system and the used protocol. As such, not only over-but also underrepresented residues can be visualized in a statistically sound manner, which further allows the user to easily analyse and interpret conserved sequence patterns in proteins. The web application and SOAP service can be found free and open to all users without the need for a login on http://iomics.ugent.be/icelogoserver/main.html.
引用
收藏
页码：W543 / W546
页数：4
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