Partial and complete spontaneous regression of testicular seminoma: clinical cases

被引：0
|
作者：
Surkova, V. S. [1 ]
Volchenko, N. N. [1 ]
Burakova, Y. A. [1 ]
Lavrova, A. M. [1 ]
Ashyrove, F. S. [1 ,2 ]
Khakimova, G. G. [3 ,4 ]
机构：
[1] Minist Hlth Russia, PA Hertzen Moscow Oncol Res Inst, Branch Natl Med Res Radiol Ctr, 3 2nd Botkinskiy Proezd, Moscow 125284, Russia
[2] Sechenov Univ, IM Sechenov First Moscow State Med Univ, Minist Hlth Russia, Build 2,8 Trubetskaya St, Moscow 119991, Russia
[3] Republican Specialized Sci & Pract Med Ctr Oncol, Tashkent City Branch, 1 Bogiston St, Tashkent 100070, Uzbekistan
[4] Tashkent Pediat Med Inst, Dept Oncol Pediat Oncol, 223 Bogishamol St, Tashkent 100140, Uzbekistan
来源：
ONKOUROLOGIYA | 2022年 / 18卷 / 02期
关键词：
spontaneous tumour regression; germ cell tumour; seminoma; metastasis; intratubular germ cell neoplasia in situ; PLAP; CD117; CD30; CANCER; TUMOR;
D O I：
10.17650/1726-9776-2022-18-2-198-205
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Spontaneous tumour regression is a rare phenomenon in which there is a complete or partial regression of the primary tumour, clinically manifested by metastatic lesions. We report a case of a 34-year-old male with partial spontaneous regression of testicular seminoma detected by a supraclavicular lymph node biopsy. He underwent inguinal orchifunicolectomy. Based on the results of histological examination, against the background of multiple complexes of intratubular germ cell neoplasia in situ, foci of invasive growth and involution were identified, indicating a spontaneously regressing testicular tumour. We report the second case of a 52-year-old male with total spontaneous regression of testicular seminoma detected by a spermatic cord biopsy. Based on the results of histological examination, against fibrosis and proliferation of Leydig cells, there are atrophy of seminiferous tubules and complexes of intratubular germ cell neoplasia in situ in part of them.
引用
收藏
页码：198 / 205
页数：8
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