Regulation of dendritic cell subsets by NKT cells

被引：4

作者：

Strominger, JL ^{[1
]}

Byrne, MC

Wilson, SB

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

[2] Genet Inst Inc, Cambridge, MA 02140 USA

[3] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

来源：

COMPTES RENDUS BIOLOGIES | 2003年 / 326卷 / 10-11期

关键词：

dendritic cell; expression profile; immune response; NKT cell; T cell;

D O I：

10.1016/j.crvi.2003.09.023

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

NKT cells expressing both invariant TCRs and NK cell receptors are an important regulatory cell subset active during initiation of innate immune responses. They are involved in a wide variety of immune responses, but the molecular details of their regulatory action are unknown. Transcriptional profiling has been used for analysis of NKT cell activation profiles, revealing that NKT cells differ from conventional T cells and would be expected to regulate immune responses by controlling dendritic cell activation. (C) 2003 Published by Elsevier SAS on behalf of Academie des sciences.

引用

页码：1045 / 1048

页数：4

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