Impediments to Clinical Research in the United States

被引：37

作者：

Kramer, J. M. ^{[1
,2
,3
]}

Smith, P. B. ^{[2
,3
,4
]}

Califf, R. M. ^{[1
,2
,3
]}

机构：

[1] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Duke Clin Res Inst, Durham, NC 27710 USA

[3] Duke Univ, Med Ctr, Duke Translat Med Inst, Durham, NC 27710 USA

[4] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2012年 / 91卷 / 03期

关键词：

IMPACT; CHALLENGES; PRIVACY; CARE;

D O I：

10.1038/clpt.2011.341

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Clinical trials are essential to the evaluation of promising scientific discoveries, but they are becoming unsustainably burdensome, threatening to deprive patients and health-care providers of new therapies and new evidence to guide the use of existing treatments. Regulations are often blamed for impeding clinical research, but there are other elements of the clinical trials enterprise that also have the potential to add burdens, through either imposed requirements or incentives that do not favor clinical research (Figure 1).(1-3)

引用

页码：535 / 541

页数：7

共 50 条

[1] Opportunities and impediments for a consolidating and expanding profession: Genetic counseling in the United States
Kenen, RH
SOCIAL SCIENCE & MEDICINE, 1997, 45 (09) : 1377 - 1386
[2] Making a Case to Reduce Legal Impediments to Midwifery Practice in the United States
Yang, Y. Tony
Kozhimannil, Katy B.
WOMENS HEALTH ISSUES, 2015, 25 (04) : 314 - 317
[3] The United States of America and Scientific Research
Hather, Gregory J.
Haynes, Winston
Higdon, Roger
Kolker, Natali
Stewart, Elizabeth A.
Arzberger, Peter
Chain, Patrick
Field, Dawn
Franza, B. Robert
Lin, Biaoyang
Meyer, Folker
Ozdemir, Vural
Smith, Charles V.
van Belle, Gerald
Wooley, John
Kolker, Eugene
PLOS ONE, 2010, 5 (08):
[4] A Comparative Study of Patients' Attitudes Toward Clinical Research in the United States and Urban and Rural China
Wu, Elizabeth
Wang, Tianyi
Lin, Tammy
Chen, Xisui
Guan, Zhe
Cao, Claudia
Rao, Huiying
Yang, Ming
Feng, Bo
Pui, Sandra
Chan, Melvin
Fu, Sherry
Lin, Andy
Wei, Lai
Lok, Anna S.
CTS-Clinical and Translational Science, 2015, 8 (02): : 123 - 131
[5] Research mobility to the United States: a bibliometric analysis
Poitras, Constance
Lariviere, Vincent
SCIENTOMETRICS, 2023, 128 (04) : 2601 - 2614
[6] Analysis of neurosurgery resident research activity in the United States
Vought, Rita
Vought, Victoria
Sames, Antonia
Shah, Shrey
Bosland, Amanda
Petrozzino, Marco
Herzog, Ava
Liu, James K.
JOURNAL OF NEUROSURGERY, 2024, 141 (05) : 1378 - 1385
[7] A Systematic Research Synthesis on Cyberbullying Interventions in the United States
Lancaster, Morgan
CYBERPSYCHOLOGY BEHAVIOR AND SOCIAL NETWORKING, 2018, 21 (10) : 593 - 602
[8] Operational Research to Improve HIV Prevention in the United States
Herbst, Jeffrey H.
Glassman, Marlene
Carey, James W.
Painter, Thomas M.
Gelaude, Deborah J.
Fasula, Amy M.
Raiford, Jerris L.
Freeman, Arin E.
Harshbarger, Camilla
Viall, Abigail H.
Purcell, David W.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2012, 59 (05) : 530 - 536
[9] Grandparenting in the United States
Meyer, Madonna Harrington
Kandic, Amra
INNOVATION IN AGING, 2017, 1 (02)
[10] Strengthening clinical cancer research in the United Kingdom
Stead, M.
Cameron, D.
Lester, N.
Parmar, M.
Haward, R.
Kaplan, R.
Maughan, T.
Wilson, R.
Campbell, H.
Hamilton, R.
Stewart, D.
O'Toole, L.
Kerr, D.
Potts, V.
Moser, R.
Darbyshire, J.
Selby, P.
BRITISH JOURNAL OF CANCER, 2011, 104 (10) : 1529 - 1534

← 1 2 3 4 5 →