Sample extraction techniques and high-performance liquid chromatographic methods for the analysis of bisphenols

Bisphenols (BPs) have attracted attention worldwide due to their distribution in environmental, biological fluids and food matrices. Therefore, the monitoring of BPs is necessary for human health. Since their occurrence in such matrices at very low concentrations different sample extraction and cleanup techniques mostly solid phase extraction (SPE) and microextraction followed by HPLC widely utilized for analysis of BPs. Different sample extraction techniques that have been used for extraction of BPs such as liquid-liquid extraction, dispersive liquid-liquid microextraction, solid phase extraction (SPE), molecularly imprinted polymers, magnetic solid phase extraction and quick, easy, cheap, effective, rugged and safe were reviewed and discussed. In this review, the sample extraction techniques and HPLC methods using various detectors that have been developed and validated so far, for analysis of BPs in biological, food and environmental samples, are overviewed and discussed.