Effect of smoking and aging on micronucleus frequencies in human exfoliated buccal cells

被引:0
作者
Konopacka, M [1 ]
机构
[1] Inst Oncol, Dept Expt & Clin Radiobiol, PL-44100 Gliwice, Poland
关键词
micronuclei; exfoliated buccal cells; smoking; aging;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In the present work the frequency of micronuclei (MN) in exfoliated buccal cells in 120 healthy individuals with relation to sex, age and smoking was investigated. Neither age nor sex showed any effect on the level of micronuclei. Smoking has shown a significant effect upon basal DNA damage. In the present study the calculated background frequency of micronuclei (parts per thousand) in oral epithelial cells of 50 smokers and 70 non-smokers were 1.50 (+/-0.47) and 0.55 (+/-0.32), respectively.
引用
收藏
页码:380 / 382
页数:3
相关论文
共 50 条
  • [41] Exploratory study on micronuclei and metanuclear abnormalities in exfoliated buccal cells of COVID-19 suspected patients
    Vishnu, B.
    Murugan, Senthil
    Kalidoss, Vinoth K.
    Sesham, Kishore
    Ramamurthy, Sarah
    Bakshi, Satvinder S.
    Francis, Yuvaraj M.
    Kasirajan, Sankaran Ponnusamy
    JOURNAL OF CYTOLOGY, 2024, 41 (01) : 28 - 33
  • [42] The nature of "broken egg" events in exfoliated human cells
    Nersesyan, Armen K.
    ACTA CYTOLOGICA, 2006, 50 (05) : 598 - 599
  • [43] EFFECT OF CIGARETTE-SMOKING ON SALIVARY EPIDERMAL GROWTH-FACTOR (EGF) AND EGF RECEPTOR IN HUMAN BUCCAL MUCOSA
    WANG, SL
    MILLES, M
    WUWANG, CY
    MARDIROSSIAN, G
    LEUNG, C
    SLOMIANY, A
    SLOMIANY, BL
    TOXICOLOGY, 1992, 75 (02) : 145 - 157
  • [44] The effect of tobacco smoking and of betel chewing with tobacco on the buccal mucosa: a cytomorphometric analysis
    Ramaesh, T
    Mendis, BRRN
    Ratnatunga, N
    Thattil, RO
    JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1999, 28 (09) : 385 - 388
  • [45] Genotoxic and Cytotoxic Effects of Cone Beam Computed Tomography and Multidetector Computed Tomography on Exfoliated Buccal Epithelial Cells
    Jahanshahiafshar, Zahra
    Ghorbani, Hakimeh
    Seyedmajidi, Maryam
    Nabahati, Mehrdad
    Gorji, Kourosh Ebrahimnejad
    Seyedmajidi, Seyedali
    Moudi, Ehsan
    IRANIAN JOURNAL OF MEDICAL SCIENCES, 2023, 48 (06) : 572 - 581
  • [46] THE INFLUENCE OF RADIATION THERAPY ON THE LEVELS OF MICRONUCLEI AND OTHER NUCLEAR ANOMALIES IN EXFOLIATED BUCCAL AND CERVIX CELLS OF CANCER PATIENTS
    Parsadanyan, G. G.
    Zalinyan, G. G.
    Khangeldyan, A. A.
    Bakhshinyan, E. M.
    Nersesyan, A. K.
    NEW ARMENIAN MEDICAL JOURNAL, 2010, 4 (04): : 59 - 62
  • [47] EFFECT OF SMOKING ON DIFFERENT BIOLOGICAL PARAMETERS IN AGING MICE
    BOROSS, M
    PENZES, L
    IZSAK, J
    RAJCZY, K
    BEREGI, E
    ZEITSCHRIFT FUR GERONTOLOGIE, 1991, 24 (02): : 76 - 80
  • [48] Basal and induced micronucleus frequencies in human lymphocytes with different GST and NAT2 genetic backgrounds
    Hernandez, Alba
    Xamena, Noel
    Gutierrez, Sara
    Velazquez, Antonia
    Creus, Amadeu
    Surralles, Jordi
    Galofre, Pere
    Marcos, Ricardo
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2006, 606 (1-2) : 12 - 20
  • [49] Micronuclei frequencies in exfoliated nasal mucosa cells from pathology and anatomy laboratory workers exposed to formaldehyde
    Burgaz, S
    Çakmak, G
    Erdem, O
    Yilmaz, M
    Karakaya, AE
    NEOPLASMA, 2001, 48 (02) : 144 - 147
  • [50] Effect of polymorphic metabolizing genes on micronucleus frequencies among benzene-exposed shoe workers in China
    Zhang, Guang-hui
    Ye, Ling-li
    Wang, Jin-wei
    Ren, Jing-chao
    Xu, Xiao-wen
    Feng, Nan-nan
    Zhou, Li-fang
    Ru, Jian-guo
    Hao, Yan-hui
    tian, Wei
    Sun, Pin
    Au, William W.
    Christiani, David C.
    Xia, Zhao-lin
    INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2014, 217 (07) : 726 - 732