Synthesis and Antimicrobial Studies of Some Novel Bis-[1,3,4]thiadiazole and Bis-thiazole Pendant to Thieno[2,3-b]thiophene Moiety

被引：34

作者：

Kheder, Nabila Abdelshafy ^{[2
]}

Mabkhot, Yahia Nasser ^{[1
]}

机构：

[1] King Saud Univ, Dept Chem, Fac Sci, Riyadh 11451, Saudi Arabia

[2] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2012年 / 13卷 / 03期

关键词：

thieno[2,3-b]thiophene; nucleophilic addition; hydrazonoyl halides; bis-thiadiazoles; bis-thiazoles; antimicrobial activity; BIOLOGICAL EVALUATION; THIOPHENE; INHIBITORS; ANTICONVULSANT; DERIVATIVES; SERIES;

D O I：

10.3390/ijms13033661

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthetic utility of 3,3'-(3,4-dimethylthieno[2,3-b]thiophene-2,5-diyl)bis (3-oxopropanenitrile) (1) in the synthesis of some novel bis-[1,3,4-thiadiazole] 6a-g and bis-thiazole 10 and 13 derivatives with thieno[2,3-b]thiophene moiety is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed promising results.

引用

页码：3661 / 3670

页数：10

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