Linking ubiquitin, parkin and synphilin-1

被引：27
|
作者：
Ciechanover, A
机构：
[1] Technion Israel Inst Technol, Bruce Rappaport Fac Med, Dept Biochem, IL-31096 Haifa, Israel
[2] Technion Israel Inst Technol, Rappaport Family Inst Res Med Sci, IL-31096 Haifa, Israel
来源：
NATURE MEDICINE | 2001年 / 7卷 / 10期
关键词：
D O I：
10.1038/nm1001-1108
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
One neuronal characteristic of Parkinson disease is the presence of Lewy bodies-intracytoplasmic accumulations of protein. A new study draws a molecular link between the formation of these bodies, the ubiquitin protein degradation system, parkin and synphilin-1.
引用
收藏
页码：1108 / 1109
页数：2
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