This paper, combining with the "5.12" Wenchuan earthquake damage data, analysis the destruction and the cause of the destruction of the frame structure folded plate staircase stair tread in the earthquake. And on this basis, this paper, taking a 5-layer framework structure office building as example and using the PMSAP finite element analysis software, establishes the spatial model with a folded plate stair components included and does the quantitative analysis, which in the end results in the variation of internal forces of the variety of stair treads under earthquake size and the changing law, and then the traditional model results is compared with the new data. Finally, this paper comes up with the design strategies for new construction and the repair and reinforcement of the reinforced concrete frame structure folded plate stair frame in the future.