Fomitopsins I and J, 24-methyl-lanostane triterpenoids from fruiting bodies of the wood-rot basidiomycete Fomitopsis sp.

被引：6

作者：

Isaka, Masahiko ^{[1
]}

Chinthanom, Panida ^{[1
]}

Suvannakad, Rapheephat ^{[1
]}

Thummarukcharoen, Tuksaporn ^{[1
]}

Peng, Tao ^{[2
]}

Liu, Ji-Kai ^{[2
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, 113 Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathumthani, Thailand

[2] South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2019年 / 29卷

基金：

中国国家自然科学基金;

关键词：

Fomitopsis; 24-Methyllanostane; Antibacterial activity; LANOSTANE TRITERPENOIDS; FUNGUS; STEROIDS; ACIDS;

D O I：

10.1016/j.phytol.2018.12.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new 24-methyl-lanostane triterpenoids, fomitopsins I (1) and J (2), were isolated together with seven known compounds (3-9), from fruiting bodies of the basidiomycete Fomitopsis species. The structures were elucidated by spectroscopic analysis. Their antibacterial and cytotoxic activities were evaluated. One of the known compounds (6) exhibited antibacterial activity against Gram-positive bacteria, Bacillus cereus (MIC 6.25 mu g/ml) and Enterococcus faecium (MIC 12.5 mu g/ml).

引用

页码：178 / 181

页数：4

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