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Care of diabetes in children and adolescents: controversies, changes, and consensus
被引:69
|作者:
Cameron, Fergus J.
[1
,2
]
Wherrett, Diane K.
[3
]
机构:
[1] Univ Melbourne, Royal Childrens Hosp, Dept Endocrinol & Diabet, Ctr Hormone Res,Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia
[2] Univ Melbourne, Dept Paediat, Fac Med Dent & Hlth Sci, Parkville, Vic 3052, Australia
[3] Univ Toronto, Hosp Sick Children, Dept Paediat, Div Endocrinol, Toronto, ON M5G 1X8, Canada
来源:
LANCET
|
2015年
/
385卷
/
9982期
基金:
美国国家卫生研究院;
英国医学研究理事会;
关键词:
INSULIN-PUMP THERAPY;
IMPROVED METABOLIC-CONTROL;
GLYCEMIC CONTROL;
PITTSBURGH EPIDEMIOLOGY;
COMPLICATIONS-TRIAL/EPIDEMIOLOGY;
ARTIFICIAL PANCREAS;
LIFE EXPECTANCY;
GLUCOSE CONTROL;
HOME-USE;
TYPE-1;
D O I:
10.1016/S0140-6736(15)60971-0
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Diabetes is one of the most common chronic medical disorders in children. The management of diabetes remains a substantial burden on children with diabetes and their families, despite improvements in treatment and rates of morbidity and mortality. Although most children with diabetes have type 1 diabetes, the increasing recognition of type 2 diabetes and genetic forms of diabetes in the paediatric population has important treatment implications. Diabetes therapy focuses strongly on targets for good metabolic control to reduce the risk of long-term complications. A parallel goal is to minimise short-term complications of hypoglycaemia and diabetic ketoacidosis. Technology offers opportunity for improvement in care, but has not yet fully lived up to its potential. New insights into the pathogenesis of diabetes and the development of new therapies have led to clinical trials aimed at the prevention of diabetes.
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页码:2096 / 2106
页数:11
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