Nosocomial outbreak of Pantoea agglomerans bacteraemia associated with contaminated anticoagulant citrate dextrose solution: new name, old bug?

被引：25

作者：

Boszczowski, I. ^{[1
]}

Nobrega de Almeida Junior, J. ^{[2
]}

Peixoto de Miranda, E. J. ^{[1
]}

Pinheiro Freire, M. ^{[1
]}

Guimaraes, T. ^{[1
]}

Chaves, C. E.

Cais, D. P. ^{[3
]}

Strabelli, T. M. V. ^{[3
]}

Risek, C. F. ^{[4
,5
]}

Soares, R. E. ^{[4
,5
]}

Rossi, F. ^{[2
]}

Costa, S. F. ^{[4
,5
]}

Levin, A. S. ^{[1
,4
,5
]}

机构：

[1] Univ Sao Paulo, Infect Control Dept, Hosp Clin, BR-05508 Sao Paulo, Brazil

[2] Univ Sao Paulo, Microbiol Lab, Hosp Clin, BR-05508 Sao Paulo, Brazil

[3] Univ Sao, Infect Control Dept, Inst Heart, Hosp Clin, Sao Paulo, Brazil

[4] Univ Sao Paulo, Dept Infect Dis, BR-05508 Sao Paulo, Brazil

[5] Univ Sao Paulo, LIM 54, BR-05508 Sao Paulo, Brazil

来源：

JOURNAL OF HOSPITAL INFECTION | 2012年 / 80卷 / 03期

关键词：

Anticoagulant citrate-dextrose; Bacteraemia; Outbreak; Pantoea agglomerans; ENTEROBACTER-AGGLOMERANS;

D O I：

10.1016/j.jhin.2011.12.006

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We describe an outbreak investigation of Pantoea agglomerans bacteraemia associated with anticoagulant citrate-dextrose 46% (ACD) solution prepared in-house. A healthy man presented with septic shock during plasmapheresis for granulocyte donation. The solution used for priming and blood samples were sent for culture. Identification of the isolate to species level was performed by gyrB sequencing. Typing was performed by pulsed-field gel electrophoresis (PFGE). In total, eight cases were identified during a three-week period. P. agglomerans was also cultured from six ACD solution bags. Isolates from patients and ACD bags were identical by PFGE. All isolates were susceptible to ampicillin, cephazolin, gentamicin, ciprofloxacin, cefepime and imipenem. (C) 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：255 / 258

页数：4

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