Antimicrobial Activity of Fungi Strains of Trichoderma from Middle Siberia

被引:9
|
作者
Sadykova, V. S. [1 ]
Kurakov, A. V. [2 ]
Kuvarina, A. E. [2 ]
Rogozhin, E. A. [1 ]
机构
[1] Gause Inst New Antibiot, Moscow 119021, Russia
[2] Moscow MV Lomonosov State Univ, Fac Biol, Moscow 119991, Russia
基金
俄罗斯科学基金会;
关键词
antifungal activity; antibacterial activity; peptaibols; antibiotics; micromycetes; fungi of Trichoderma genus; SECONDARY METABOLITES; ANTAGONISTIC FUNGI;
D O I
10.1134/S000368381503014X
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The antibiotic activity in 42 strains of 8 species of the Trichoderma genus (T. asperellum, T. viride, T. hamatum,T. koningii, T. atroviride, T. harzianum, T. Citrinoviride, and T. longibrachiatum) isolated from different Siberian ecotops was studied. It was shown that these species differ in the degree of their antibacterial and antifungal activity. The chosen strain, T. citrinoviride TV4-1, exhibited high activity and a wide range of actions against the opportunistic and pathogenic fungi of the Aspergillus and Candida albicans genus; bacteria, including methicillin-resistant Staphylococcus aureus; and cancer cells. According to mass and IR spectrometry data and the spectrum of biological action, peptaibols are probably the most active compounds in the strain culture extracts.
引用
收藏
页码:355 / 361
页数:7
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