Real-time elastography for the differentiation of benign and malignant breast lesions: a meta-analysis

被引：101
作者：
Gong, Xia [1 ]
Xu, Qiuhua [1 ]
Xu, Zhengliang [1 ]
Xiong, Ping [1 ]
Yan, Weili [2 ]
Chen, Yazhu [3 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Ultrasound, Shanghai 200011, Peoples R China
[2] Pudong Inst Hlth Dev, Shanghai 200129, Peoples R China
[3] Shanghai Jiao Tong Univ, Dept Biomed Engn, Shanghai 200240, Peoples R China
来源：
BREAST CANCER RESEARCH AND TREATMENT | 2011年 / 130卷 / 01期
基金：
中国国家自然科学基金; 上海市自然科学基金;
关键词：
RTE; Breast lesions; Sensitivity; Specificity; Meta-analysis; B-MODE ULTRASOUND; US ELASTOGRAPHY; SONOGRAPHIC ELASTOGRAPHY; DIAGNOSTIC PERFORMANCE; MASSES; SONOELASTOGRAPHY; MAMMOGRAPHY; EXPERIENCE; CLASSIFICATION; BIAS;
D O I：
10.1007/s10549-011-1745-2
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The prognostic significance of ultrasound real-time elastography (RTE) in patients with breast lesions is controversial. There are two different diagnostic methods: the elasticity score (ES) and the strain ratio (SR). A meta-analysis was performed using a random-effect model to assess the overall sensitivity and specificity of RTE in the differentiation of breast lesions. MEDLINE, EMBASE, PubMed, and the Cochrane Library before February 2011 were searched. A total of 22 studies, which included 4,713 breast nodules in 4,266 patients were analyzed. The overall mean sensitivity and specificity for the diagnosis of malignant breast lesions by RTE were 0.834 [95% confidence interval (CI) 0.814-0.853] and 0.842 (95% CI, 0.829-0.854) for ES, and 0.883 (95% CI, 0.844-0.916) and 0.814 (95% CI, 0.786-0.839) for SR, respectively. RTE has a high sensitivity and specificity in the evaluation of breast lesions and can potentially reduce unnecessary breast biopsies.
引用
收藏
页码：11 / 18
页数：8
相关论文
共 40 条
[1]   Statistics Notes - Interaction revisited: the difference between two estimates [J].
Altman, DG ;
Bland, JM .
BMJ-BRITISH MEDICAL JOURNAL, 2003, 326 (7382) :219-219
[2]   Real-Time Ultrasound Elasticity of the Breast Initial Clinical Results [J].
Barr, Richard G. .
ULTRASOUND QUARTERLY, 2010, 26 (02) :61-66
[3]   Does blinding of readers affect the results of meta-analyses? [J].
Berlin, JA .
LANCET, 1997, 350 (9072) :185-186
[4]   Differentiating benign from malignant solid breast masses with US strain imaging [J].
Burnside, Elizabeth S. ;
Hall, Timothy J. ;
Sommer, Amy M. ;
Hesley, Gina K. ;
Sisney, Gale A. ;
Svensson, William E. ;
Fine, Jason P. ;
Jiang, Jinfeng ;
Hangiandreou, Nicholas J. .
RADIOLOGY, 2007, 245 (02) :401-410
[5]  
Fleury EDC, 2009, DIAGN INTERV RADIOL, V15, P96
[6]   Sonographic features of nonpalpable breast cancer: A study based on ultrasound-guided wire-localized surgical biopsies [J].
Chiou, See-Ying ;
Chou, Yi-Hong ;
Chiou, Hong-Jen ;
Wang, Hsin-Kai ;
Tiu, Chui-Mei ;
Tseng, Ling-Ming ;
Chang, Cheng-Yen .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2006, 32 (09) :1299-1306
[7]   Nonpalpable breast masses: Evaluation by US elastography [J].
Cho, Nariya ;
Moon, Woo Kyung ;
Park, Jeong Seon ;
Cha, Joo Hee ;
Jang, Mijung ;
Seong, Min Hyun .
KOREAN JOURNAL OF RADIOLOGY, 2008, 9 (02) :111-118
[8]  
Cho N, 2010, J ULTRAS MED, V29, P1
[9]   Real-time US elastography in the differentiation of suspicious microcalcifications on mammography [J].
Cho, Nariya ;
Moon, Woo Kyung ;
Park, Jeong-Seon .
EUROPEAN RADIOLOGY, 2009, 19 (07) :1621-1628
[10]   Differentiation of benign from malignant nonpalpable breast masses: A comparison of computer-assisted quantification and visual assessment of lesion stiffness with the use of sonographic elastography [J].
Chung, Se Yeong ;
Moon, Woo Kyung ;
Choi, Ji Won ;
Cho, Nariya ;
Jang, Mijung ;
Kim, Kwang Gi .
ACTA RADIOLOGICA, 2010, 51 (01) :9-14
1234