European-wide distribution of Pseudomonas aeruginosa clone C

被引：23
作者：
Dinesh, SD
Grundmann, H
Pitt, TL
Römling, U [1 ]
机构：
[1] GBF German Res Ctr Biotechnol, Div Cell & Immune Biol, Res Grp Clonal Variabil, Braunschweig, Germany
[2] Univ Nottingham Hosp, Queens Med Ctr, Div Microbiol & Infect Dis, Nottingham NG7 2UH, England
[3] Cent Publ Hlth Lab, Lab Hosp Infect, London NW9 5HT, England
[4] Karolinska Inst, MTC, SE-17177 Stockholm, Sweden
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2003年 / 9卷 / 12期
关键词：
Pseudomonas aeruginosa; epidemiology; pulsed-field gel electrophoresis; plasmid; genetic island;
D O I：
10.1111/j.1469-0691.2003.00793.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A collection of 77 epidemiologically unrelated Pseudomonas aeruginosa isolates was screened for the occurrence of clone C isolates by the appearance of characteristic SpeI fragment patterns obtained by pulsed-field gel electrophoresis. Three strains with a clone C characteristic SpeI fragment pattern were found which also harbored the clone C-specific plasmid either in the free form or chromosomally integrated. Genomic islands were detected in the new clone C strains, as in already characterized clone C strains. Clone C not only infected cystic fibrosis patients throughout Europe, but was also found in the UK as an isolate in urinary tract infections and in peritoneal dialysis fluid, in addition to an otitis media isolate. Therefore, P. aeruginosa clone C is widely distributed in Europe, with a broad pathogenic potential.
引用
收藏
页码：1228 / 1233
页数：6
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