Voluntary running exercise alters microbiota composition and increases n-butyrate concentration in the rat cecum

被引:298
作者
Matsumoto, Megumi [1 ,2 ]
Inoue, Ryo [2 ]
Tsukahara, Takamitsu [3 ]
Ushida, Kazunari [4 ]
Chiji, Hideyuki [5 ]
Matsubara, Noritaka [6 ]
Hara, Hiroshi [1 ]
机构
[1] Hokkaido Univ, Lab Nutrit Biochem, Div Appl Biosci, Grad Sch Agr, Sapporo, Hokkaido 0608589, Japan
[2] Hokkaido Univ, Meiji Dairies Res Chair, Creat Res Initiat Sousei, Sapporo, Hokkaido 0010021, Japan
[3] Kyoto Inst Nutr & Pathol, Kyoto 6100231, Japan
[4] Kyoto Prefectural Univ, Lab Anim Sci, Kyoto 6068522, Japan
[5] Fuji Womens Univ, Dept Food Sci & Human Nutr, Fac Human Life Sci, Ishikari, Hokkaido 0613204, Japan
[6] Combi Corp, Saitama 3380832, Japan
关键词
cecal microbiota; voluntary running exercise; n-butyrate; hierarchical cluster analysis;
D O I
10.1271/bbb.70474
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effects of voluntary wheel-running exercise on cecal microbiota and short-chain fatty acid production were investigated in rats. The microbiota composition was notably different between the exercised and sedentary rats. Furthermore, the exercised rats showed a significantly higher n-butyrate concentration than the sedentary rats. This alteration of the cecal microbial environment may contribute to the beneficial effect of exercise on gastrointestinal disorders.
引用
收藏
页码:572 / 576
页数:5
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