Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force

被引：76

作者：

Filippou, Georgios ^{[1
]}

Scire, Carlo A. ^{[18
]}

Damjanov, Nemanja ^{[6
]}

Adinolfi, Antonella ^{[1
]}

Carrara, Greta ^{[19
]}

Picerno, Valentina ^{[1
]}

Toscano, Carmela ^{[1
]}

Bruyn, George A. ^{[7
]}

D'Agostino, Maria Antonietta ^{[8
,9
]}

Delle Sedie, Andrea ^{[2
]}

Filippucci, Emilio ^{[3
]}

Gutierrez, Marwin ^{[10
]}

Micu, Mihaela ^{[11
]}

Moller, Ingrid ^{[13
]}

Naredo, Esperanza ^{[14
,15
]}

Pineda, Carlos ^{[10
]}

Porta, Francesco ^{[4
]}

Schmidt, Wolfgang A. ^{[20
]}

Terslev, Lene ^{[16
]}

Vlad, Violeta ^{[12
]}

Zufferey, Pascal ^{[17
]}

Iagnocco, Annamaria ^{[5
]}

机构：

[1] Univ Siena, Siena, Italy

[2] Univ Pisa, Pisa, Italy

[3] Univ Politecn Marche, Rheumatol, Jesi, Italy

[4] San Jacopo Hosp, Internal Med Div, Pistoia, Italy

[5] Univ Turin, Rheumatol, Turin, Italy

[6] Univ Belgrade, Rheumatol, Belgrade, Serbia

[7] MC Groep, Dept Rheumatol, Rheumatol, Lelystad, Netherlands

[8] Hop Ambroise Pare, AP HP, Rheumatol Dept, Boulogne, France

[9] Versailles St Quentin Univ, UFR Simone Veil, INSERM U1173, Lab Excellence INFLAMEX, St Quentin En Yvelines, France

[10] Inst Nacl Rehabil Luis Guillermo Ibarra Ibarra, Div Musculoskeletal & Rheumat Dis, Mexico City, DF, Mexico

[11] Rehabil Clin Hosp, Cluj Napoca, Romania

[12] Sf Maria Hosp, Bucharest, Romania

[13] Univ Barcelona, Inst Poal, Barcelona, Spain

[14] Hosp Univ Fdn Jimenez Deaz, Joint & Bone Res Unit, Dept Rheumatol, Madrid, Spain

[15] Univ Autonoma Madrid, Madrid, Spain

[16] Rigshosp, Ctr Rheumatol & Spine Dis, Copenhagen, Denmark

[17] Lausanne Univ Hosp, Lausanne, Switzerland

[18] SIR Epidemiol Unit, Rheumatol, Milan, Italy

[19] SIR Epidemiol Unit, Milan, Italy

[20] Charite, Immanuel Krankenhaus Berlin, Med Ctr Rheumatol Berlin Buch, Berlin, Germany

来源：

JOURNAL OF RHEUMATOLOGY | 2017年 / 44卷 / 11期

关键词：

CHONDROCALCINOSIS; ULTRASONOGRAPHY; KNEE OSTEOARTHRITIS; OSTEOARTHRITIS; KNEE; DIAGNOSIS; CHONDROCALCINOSIS; AGREEMENT; GOUT;

D O I：

10.3899/jrheum.161057

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To define the ultrasonographic characteristics of calcium pyrophosphate crystal (CPP) deposits in joints and periarticular tissues and to evaluate the intra-and interobserver reliability of expert ultrasonographers in the assessment of CPP deposition disease (CPPD) according to the new definitions. Methods. After a systematic literature review, a Delphi survey was circulated among a group of expert ultrasonographers, who were members of the CPPD Ultrasound (US) Outcome Measures in Rheumatology (OMERACT) subtask force, to obtain definitions of the US characteristics of CPPD at the level of fibrocartilage (FC), hyaline cartilage (HC), tendon, and synovial fluid (SF). Subsequently, the reliability of US in assessing CPPD at knee and wrist levels according to the agreed definitions was tested in static images and in patients with CPPD. Cohen's kappa was used for statistical analysis. Results. HC and FC of the knee yielded the highest interobserver k values among all the structures examined, in both the Web-based (0.73 for HC and 0.58 for FC) and patient-based exercises (0.55 for the HC and 0.64 for the FC). Kappa values for the other structures were lower, ranging from 0.28 in tendons to 0.50 in SF in the static exercise and from 0.09 (proximal patellar tendon) to 0.27 (triangular FC of the wrist) in the patient-based exercise. Conclusion. The new OMERACT definitions for the US identification of CPPD proved to be reliable at the level of the HC and FC of the knee. Further studies are needed to better define the US characteristics of CPPD and optimize the scanning technique in other anatomical sites.

引用

页码：1744 / 1749

页数：6

共 18 条

[1] How to Choose Core Outcome Measurement Sets for Clinical Trials: OMERACT 11 Approves Filter 2.0 [J].