A green and convenient synthesis of 2-aroylbenzofurans in aqueous media

被引：6

作者：

Kamboj, Ramesh C. ^{[1
]}

Sharma, Geeta ^{[1
]}

Jindal, Pooja ^{[1
]}

Arora, Rita ^{[1
]}

Kumar, Dinesh ^{[1
]}

Kumar, Suresh ^{[1
]}

Kumar, Parvin ^{[1
]}

机构：

[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2017年 / 10卷

关键词：

Benzofuran; Aqueous medium; Tetra-n-butylammoniumbromide; alpha-Bromoketones; Rap-Stoermer reaction; BENZOFURAN-BASED HETEROCYCLES; ONE-POT SYNTHESIS; WATER; EFFICIENT; ANTICONVULSANT; DERIVATIVES; PHENOLS; INDOLES; ROUTE;

D O I：

10.1016/j.arabjc.2013.12.013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A green and convenient synthesis of some 2-aroylbenzofurans has been developed via the Rap-Stoermer type reaction between o-hydroxyacetophenones and alpha-bromoketones in water using tetra-n-butylammoniumbromide as a phase transfer catalyst. This protocol promises the advantages of environmentally benign conditions i.e. use of water as reaction media, short reaction time, high yield and operational convenience. The products were obtained in appreciable high yields and their structures have been arrived at by the spectroscopic (FTIR, NMR and Mass) studies. The tentative mechanism of the reaction cascade has been presented. (C) 2013 King Saud University. Production and hosting by Elsevier B.V.

引用

页码：S3190 / S3196

页数：7

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