Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics

被引：21

作者：

Ernest, Umeorah ^{[1
]}

Chen, Hai-Yan ^{[1
]}

Xu, Ming-Jun ^{[1
]}

Taghipour, Yasamin Davatgaran ^{[2
]}

Bin Asad, Muhammad Hassham Hassan ^{[3
]}

Rahimi, Roja ^{[4
]}

Murtaza, Ghulam ^{[5
]}

机构：

[1] China Pharmaceut Univ, Sch Engn, Dept Biomed Engn, Nanjing 210009, Peoples R China

[2] Tabriz Univ Med Sci, Sch Adv Med Sci, Dept Med Nanotechnol, Tabriz 1416663547, Iran

[3] COMSATS Univ Islamabad, Dept Pharm, Abbottabad Campus 22060, Islamabad, Pakistan

[4] Univ Tehran Med Sci, Sch Tradit Med, Dept Tradit Pharm, Tehran 5165665931, Iran

[5] COMSATS Univ Islamabad, Dept Pharm, Lahore Campus 54600, Islamabad, Pakistan

来源：

MOLECULES | 2018年 / 23卷 / 11期

关键词：

cancer therapeutics; polymeric carriers; nanoparticles; polyphenols; cell lines; TARGETED DRUG-DELIVERY; BLOCK-COPOLYMER MICELLES; IN-VITRO; CARBON NANOTUBES; CO-DELIVERY; CHITOSAN NANOPARTICLES; MAGNETIC NANOPARTICLES; MULTIDRUG-RESISTANCE; ANTICANCER ACTIVITY; MIXED MICELLES;

D O I：

10.3390/molecules23112787

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent evidence has extensively demonstrated the anticancer potential of nutraceuticals, including plant polyphenols. Polymeric nanocarrier systems have played an important role in improving the physicochemical and pharmacological properties of polyphenols, thus ameliorating their therapeutic effectiveness. This article summarizes the benefits and shortcomings of various polymeric systems developed for the delivery of polyphenols in cancer therapy and reveals some ideas for future work.

引用

页数：21

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