Croup as a Manifestation of SARS-CoV-2 Omicron Variant Infection in Young Children

被引：22

作者：

Choi, Youn Young ^{[1
]}

Kim, You Sun ^{[1
]}

Lee, Seong Yong ^{[2
]}

Sim, Jiwoo ^{[3
]}

Choe, Young June ^{[4
]}

Han, Mi Seon ^{[2
]}

机构：

[1] Natl Med Ctr, Dept Pediat, Seoul, South Korea

[2] Seoul Natl Univ, Dept Pediat, Seoul Metropolitan Govt, Boramae Med Ctr, 20 Boramae Ro 5 Gil, Seoul 07061, South Korea

[3] Seoul Metropolitan Govt, Infect Dis Control Div, Seoul, South Korea

[4] Korea Univ, Dept Pediat, Anam Hosp, Seoul, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2022年 / 37卷 / 20期

关键词：

Croup; Children; SARS-CoV-2; COVID-19; Omicron;

D O I：

10.3346/jkms.2022.37.e140

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Croup is an acute upper respiratory disease primarily caused by the parainfluenza virus. Owing to inflammation and edema of the upper airways, children present with barky cough and stridor, and some may experience respiratory distress. We investigated children aged < 5 years with coronavirus disease 2019 (COVID-19) admitted to two hospitals in Seoul, South Korea, and observed a spike in croup cases during the omicron surge. Among the 569 children admitted from March 1, 2021 to February 25, 2022, 21 children (3.7%) had croup, and the proportion of croup cases was significantly higher during the omicron wave than that during the delta wave (12.4% vs. 1.2%, P < 0.001). With the immediate administration of corticosteroids and epinephrine via nebulizer, the symptoms improved rapidly. During the current omicron surge, careful monitoring of the symptoms of croup in young children is needed for the diagnosis of COVID-19 and its timely management.

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