Much IDO about pregnancy

被引:52
作者
Bonney, EA [1 ]
Matzinger, P
机构
[1] Emory Univ, Sch Med, Dept Gynecol & Obstet, Atlanta, GA 30303 USA
[2] NIAID, Cellular & Mol Immunol Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/2624
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A recent study suggests that immunosuppression mediated by IDO, an enzyme that catabolizes tryptophan, may prevent rejection of the fetus by the maternal immune system.
引用
收藏
页码:1128 / 1129
页数:2
相关论文
共 3 条
[1]   TOLERANCE, DANGER, AND THE EXTENDED FAMILY [J].
MATZINGER, P .
ANNUAL REVIEW OF IMMUNOLOGY, 1994, 12 :991-1045
[2]  
MEDAWAR PB, 1953, SYM SOC EXP BIOL, V7, P320
[3]   Prevention of allogeneic fetal rejection by tryptophan catabolism [J].
Munn, DH ;
Zhou, M ;
Attwood, JT ;
Bondarev, I ;
Conway, SJ ;
Marshall, B ;
Brown, C ;
Mellor, AL .
SCIENCE, 1998, 281 (5380) :1191-1193