Electric field of a six-needle array electrode used in drug and DNA delivery in vivo:: Analytical versus numerical solution

被引：47
作者：
Dev, SB
Dhar, D
Krassowska, W [1 ]
机构：
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[2] Tata Inst Fundamental Res, Dept Theoret Phys, Bombay 400005, Maharashtra, India
[3] Gene Delivery & Express Sci, San Diego, CA 92122 USA
来源：
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 2003年 / 50卷 / 11期
基金：
美国国家科学基金会;
关键词：
electroporation; electric field; finite element; multipole expansion;
D O I：
10.1109/TBME.2003.818467
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We present an analytical solution for the electrical potential and field established by a six-needle array electroporation electrode, which is used in vivo for cancer treatment and DNA delivery. The analytical solution closely matches the,numerical solution obtained with the finite element method: the mean error is less than 0.6%.
引用
收藏
页码：1296 / 1300
页数：5
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