Facile synthesis of silver@graphene oxide nanocomposites and their enhanced antibacterial properties

被引:299
作者
Xu, Wei-Ping [1 ,2 ]
Zhang, Le-Cheng [1 ]
Li, Jian-Ping [2 ]
Lu, Yang [1 ]
Li, Hui-Hui [1 ]
Ma, Yi-Ni [2 ]
Wang, Wei-Di [2 ]
Yu, Shu-Hong [1 ]
机构
[1] Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei Natl Lab Phys Sci Microscale, Dept Chem,Div Nanomat & Chem, Hefei 230026, Anhui, Peoples R China
[2] Anhui Univ Tradit Chinese Med, Dept Pharm, Hefei 230038, Peoples R China
基金
中国国家自然科学基金; 对外科技合作项目(国际科技项目);
关键词
ESCHERICHIA-COLI; GREEN SYNTHESIS; NANOPARTICLES; METAL; AG; COPPER; AU;
D O I
10.1039/c0jm03376f
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Uniform and water-soluble Ag@reduced graphene oxide (Ag@rGO) nanocomposites can be prepared by a facile approach in the absence of additional reductants, which display much better antibacterial properties than that of pure silver nanoparticles synthesized by microwave irradiation, and an equivalent antibacterial effect in comparison with that of the general antibacterial drug ampicillin. Their skin irritation tests with the use of rat models are taken in order to explore the toxicity of this nanocomposite, which confirm that no oedema or erythema appears on the injured rat skin after exposure to the as-prepared Ag@rGO nanocomposites.
引用
收藏
页码:4593 / 4597
页数:5
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