Notch signaling: direct or what?

被引：94
作者：
Weinmaster, G [1 ]
机构：
[1] Univ Calif Los Angeles, Sch Med, Dept Biol Chem, Los Angeles, CA 90095 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 04期
关键词：
D O I：
10.1016/S0959-437X(98)80115-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Notch signaling has been implicated in a wide variety of processes from cell-fate decisions, tissue patterning and morphogenesis to human diseases and cancer. A model for Notch directly regulating gene expression has been proposed and at least two signaling pathways have been identified; however, the molecular mechanism(s) by which Notch signaling produces so many outcomes remains unclear.
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收藏
页码：436 / 442
页数：7
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