Hydrodynamic radii of polyethylene glycols in different solvents determined from viscosity measurements

被引：31

作者：

Dohmen, Monique P. J. ^{[1
]}

Pereira, Ana M. ^{[1
]}

Timmer, J. Martin K. ^{[2
]}

Benes, Nieck E. ^{[1
]}

Keurentjes, Jos T. F. ^{[1
]}

机构：

[1] Eindhoven Univ Technol, Dept Chem Engn & Chem, Proc Dev Grp, NL-5600 MB Eindhoven, Netherlands

[2] ETD&C Bv, NL-6710 AC Ede, Netherlands

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2008年 / 53卷 / 01期

关键词：

D O I：

10.1021/je700355n

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The hydrodynamic radius, rh, of-low molar mass polyethylene glycol, MPEG = (200 to 1000) g.mol(-1), in a homologous series of primary alcohols, acetone, and toluene has been determined from viscosity measurements. The viscosity data have been collected using a fast one-point method as well as a more generally used multipoint method. The results for both approaches are in good agreement. For a given average molar mass of PEG, r(h) is the largest in acetone, methanol, and toluene and shows a decrease with the chain length of the alcohol. For the solvents studied, rh shows an increase with MPEG that can be described adequately by the two-parameter Mark-Houwink equation for MPEG = (400 to 1000) g . mol(-1). In the range T = (298.2 to 323.2) K, the influence of the temperature is not significant.

引用

页码：63 / 65

页数：3

共 15 条

[1] The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation [J].

Armstrong, JK ;

Wenby, RB ;

Meiselman, HJ ;

Fisher, TC .

BIOPHYSICAL JOURNAL, 2004, 87 (06) :4259-4270

[2] Hydration study of PEG/water mixtures by quasi elastic light scattering, acoustic and rheological measurements [J].

Branca, C ;

Magazù, S ;

Maisano, G ;

Migliardo, F ;

Migliardo, P ;

Romeo, G .

JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (39) :10272-10276

[3] Improvement of a method for the characterization of ultrafiltration membranes by measurements of tracers retention [J].

Causserand, C ;

Rouaix, S ;

Akbari, A ;

Aimar, P .

JOURNAL OF MEMBRANE SCIENCE, 2004, 238 (1-2) :177-190

[4] Polyethylene glycol and solutions of polyethylene glycol as green reaction media [J].

Chen, J ;

Spear, SK ;

Huddleston, JG ;

Rogers, RD .

GREEN CHEMISTRY, 2005, 7 (02) :64-82

[5] Prediction of the viscosity radius and the size exclusion chromatography behavior of PEGylated proteins [J].

Fee, CJ ;

Van Alstine, JM .

BIOCONJUGATE CHEMISTRY, 2004, 15 (06) :1304-1313

[6] Crystallization of IgG1 by mapping its liquid-liquid phase separation curves [J].

Jim, Adam Idu ;

Goh, Lin-Tang ;

Oh, Steve K. W. .

BIOTECHNOLOGY AND BIOENGINEERING, 2006, 95 (05) :911-918

[7] Pegylation of proteins and bioactive substances for medical and technical applications [J].

Kodera, Y ;

Matsushima, A ;

Hiroto, M ;

Nishimura, H ;

Ishii, A ;

Ueno, T ;

Inada, Y .

PROGRESS IN POLYMER SCIENCE, 1998, 23 (07) :1233-1271

[8] AN APPROPRIATE MOLECULAR-SIZE PARAMETER FOR POROUS MEMBRANES CALIBRATION [J].

MEIRELES, M ;

BESSIERES, A ;

ROGISSART, I ;

AIMAR, P ;

SANCHEZ, V .

JOURNAL OF MEMBRANE SCIENCE, 1995, 103 (1-2) :105-115

[9] MOLECULAR-SIZE AND SOLVATION OF LOW-MOLECULAR WEIGHT POLY(ETHYLENE OXIDE) AND PHENOL FORMALDEHYDE RESOLS IN DIFFERENT SOLVENTS [J].

RIEDL, B ;

VOHL, MJ ;

CALVE, L .

JOURNAL OF APPLIED POLYMER SCIENCE, 1990, 39 (02) :341-353

[10] Single-molecule mass spectrometry in solution using a solitary nanopore [J].

Robertson, Joseph W. F. ;

Rodrigues, Claudio G. ;

Stanford, Vincent M. ;

Rubinson, Kenneth A. ;

Krasilnikov, Oleg V. ;

Kasianowicz, John J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (20) :8207-8211

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