Cholangiocarcinoma: New Insights into Disease Pathogenesis and Biology

被引:62
作者
Braconi, Chiara [1 ]
Patel, Tushar [1 ]
机构
[1] Ohio State Univ, Med Ctr, Dept Internal Med, Columbus, OH 43210 USA
基金
美国国家卫生研究院;
关键词
Biliary tract cancers; Liver flukes; Liver cancers; PRIMARY SCLEROSING CHOLANGITIS; MALIGNANT HUMAN CHOLANGIOCYTES; B-VIRUS-INFECTION; INTRAHEPATIC CHOLANGIOCARCINOMA; OPISTHORCHIS-VIVERRINI; UNITED-STATES; RISK-FACTORS; HEPATITIS-C; GENE-EXPRESSION; GROWTH-FACTOR;
D O I
10.1016/j.idc.2010.07.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cholangiocarcinomas are rare malignant tumors whose incidence is increasing worldwide. Risk factors for this malignancy include both infectious and non-infectious diseases characterized by chronic inflammation of the bile duct epithelia. Diagnosis of these. cancers remains difficult because of the lack of sensitive diagnostic tests. The prognosis is poor probably because of the lack of effective treatments for unresectable cancer.
引用
收藏
页码:871 / +
页数:15
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