Cobalt and Copper Co-Catalyzed Three-Component Reactions for the Synthesis of 1,3,4-Trisubstituted Pyrazoles

被引：4

作者：

Wei, Daidong ^{[1
]}

Ma, Haojie ^{[1
]}

Zhou, Xiaoqiang ^{[1
]}

Shi, Chong ^{[1
]}

Luo, Xinliang ^{[1
]}

Huang, Guosheng ^{[1
]}

机构：

[1] Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou, Gansu, Peoples R China

来源：

CHEMISTRYSELECT | 2017年 / 2卷 / 22期

关键词：

cobalt; copper; hydrazones; multicomponent reaction; pyrazoles; POTENTIAL ANTIMICROBIAL AGENTS; N BOND FORMATION; 1,3,5-TRISUBSTITUTED PYRAZOLES; BIOLOGICAL EVALUATION; 3+2 CYCLOADDITIONS; ESTROGEN-RECEPTOR; DERIVATIVES; HYDRAZONES; NITROOLEFINS; CYCLOOXYGENASE-2;

D O I：

10.1002/slct.201700987

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel cobalt and copper co-catalyzed for exclusive synthesis of 1,3,4-trisubstituted pyrazoles via a one-pot reaction of hydrazones with nitromethane and aldehydes has been reported. Proper conditions without additional oxidants, broad substrate scope and easily obtained starting materials make this protocol promising and practical.

引用

收藏

页码：6231 / 6234

页数：4

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