C-H Bond Functionalization in the Synthesis of Fused 1,2,3-Triazoles

被引：56
作者：
Panteleev, Jane [1 ]
Geyer, Karolin [1 ]
Aguilar-Aguilar, Angelica [1 ]
Wang, Letian [1 ]
Lautens, Mark [1 ]
机构：
[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 22期
基金：
加拿大自然科学与工程研究理事会;
关键词：
ONE-POT REACTION; SOLID-PHASE; CYCLOADDITION; ARYLATION; HETEROCYCLES; ROUTE; AZIDE; CONSTRUCTION; PHENANTHRENE; ANNULATION;
D O I：
10.1021/ol102342y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.
引用
收藏
页码：5092 / 5095
页数：4
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