C-H Bond Functionalization in the Synthesis of Fused 1,2,3-Triazoles

被引：56

作者：

Panteleev, Jane ^{[1
]}

Geyer, Karolin ^{[1
]}

Aguilar-Aguilar, Angelica ^{[1
]}

Wang, Letian ^{[1
]}

Lautens, Mark ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 22期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ONE-POT REACTION; SOLID-PHASE; CYCLOADDITION; ARYLATION; HETEROCYCLES; ROUTE; AZIDE; CONSTRUCTION; PHENANTHRENE; ANNULATION;

D O I：

10.1021/ol102342y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.

引用

页码：5092 / 5095

页数：4

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