An ontology-driven, case-based clinical decision support model for removable partial denture design

被引:36
作者
Chen, Qingxiao [1 ,2 ,3 ,4 ,5 ]
Wu, Ji [6 ]
Li, Shusen [6 ]
Lyu, Peijun [1 ,2 ,3 ,4 ,5 ]
Wang, Yong [1 ,2 ,3 ,4 ,5 ]
Li, Miao [6 ]
机构
[1] Peking Univ, Sch & Hosp Stomatol, Ctr Digital Dent, 22 Zhongguancun Ave South, Beijing 100081, Peoples R China
[2] Peking Univ, Sch & Hosp Stomatol, Dept Prosthodont, 22 Zhongguancun Ave South, Beijing 100081, Peoples R China
[3] Natl Engn Lab Digital & Mat Technol Stomatol, 22 Zhongguancun Ave South, Beijing 100081, Peoples R China
[4] Minist Hlth, Res Ctr Engn & Technol Digital Dent, 22 Zhongguancun Ave South, Beijing 100081, Peoples R China
[5] Beijing Key Lab Digital Stomatol, 22 Zhongguancun Ave South, Beijing 100081, Peoples R China
[6] Tsinghua Univ, Tsinghua Rohm Elect Engn Hall 8-301, Beijing 100084, Peoples R China
关键词
SYSTEMS; PROTEGE;
D O I
10.1038/srep27855
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient's oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application.
引用
收藏
页数:8
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