Angiosarcoma: a review of diagnosis and current treatment

被引：14
作者：
Cao, Jun [1 ]
Wang, Jiale [2 ]
He, Chiyu [2 ]
Fang, Meiyu [1 ]
机构：
[1] Univ Chinese Acad Sci, Dept Comprehens Med Oncol, Key Lab Head & Neck Canc Translat Res Zhejiang Pr, Canc Hosp,Zhejiang Canc Hosp, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Chinese Med Univ, Clin Med Coll 2, Hangzhou, Zhejiang, Peoples R China
来源：
AMERICAN JOURNAL OF CANCER RESEARCH | 2019年 / 9卷 / 11期
关键词：
Angiosarcoma; aetiology; diagnosis; prognostic factors; chemotherapy; targeted; RADIATION-INDUCED ANGIOSARCOMA; CONTRAST-ENHANCED ULTRASOUND; CUTANEOUS ANGIOSARCOMA; CARDIAC ANGIOSARCOMA; GENE AMPLIFICATION; PROGNOSTIC-FACTORS; MYC; PACLITAXEL; OUTCOMES; THERAPY;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Angiosarcoma is a highly malignancy of endothelial tumor and represents 1-2% of all soft tissue sarcomas in humans. The aetiology of angiosarcoma is not clear but there are definite risk factors including chronic lymphoedema, history of radiation, environmental carcinogens and certain familial syndromes. Ultrasound, CT and MR are diagnostic tools, but final diagnosis requires pathological and immunohistochemical confirmation. The conventional options of treatment include surgery, radiotherapy and chemotherapy. Targeted medicines and immunotherapy have been studied as promising treatment of angiosarcoma. The goal of this review is to summarize the current data regarding of angiosarcoma and its clinical presentation and management, providing a useful clinical tool to explore the optimal treatment.
引用
收藏
页码：2303 / 2313
页数：11
相关论文
共 93 条
[81]   Surgical therapy of primary hepatic angiosarcoma [J].
Tripke, Verena ;
Heinrich, Stefan ;
Huber, Tobias ;
Mittler, Jens ;
Hoppe-Lotichius, Maria ;
Straub, Beate K. ;
Lang, Hauke .
BMC SURGERY, 2019, 19
[82]   Surgically Diagnosed Primary Hepatic Angiosarcoma [J].
Tsunematsu, Seiji ;
Muto, Shuichi ;
Oi, Hiroki ;
Naka, Tomoaki ;
Kitagataya, Takashi ;
Sasaki, Rui ;
Taya, Yoko ;
Baba, Urara ;
Tsukamoto, Yuki ;
Uemura, Kazuhito ;
Kimura, Toshio ;
Ohara, Yukio .
INTERNAL MEDICINE, 2018, 57 (05) :687-691
[83]   "Sun Ray" Appearance in a Case of Cardiac Angiosarcoma: A Comparison of MRI and PET/CT [J].
Tudos, Zbynek ;
Kocher, Martin ;
Cerna, Marie ;
Odstrcil, Frantisek ;
Prouzova, Zuzana ;
Formanek, Radim ;
Precek, Jan .
MAGNETIC RESONANCE IN MEDICAL SCIENCES, 2017, 16 (02) :176-180
[84]   A new case of radiation-induced breast angiosarcoma [J].
Verdura, Vincenzo ;
Di Pace, Bruno ;
Concilio, Marina ;
Guastafierro, Antonio ;
Fiorillo, Gabriella ;
Alfano, Luigi ;
Nicoletti, Giovanni Francesco ;
Savastano, Clementina ;
Cascone, Anna Maria ;
Rubino, Corrado .
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2019, 60 :152-155
[85]   Tumor angiogenesis and vascular normalization: alternative therapeutic targets [J].
Viallard, Claire ;
Larrivee, Bruno .
ANGIOGENESIS, 2017, 20 (04) :409-426
[86]   Angiosarcoma after radiotherapy: a cohort study of 332 163 Finnish cancer patients [J].
Virtanen, A. ;
Pukkala, E. ;
Auvinen, A. .
BRITISH JOURNAL OF CANCER, 2007, 97 (01) :115-117
[87]   Clinicopathological features and prognostic factors in angiosarcoma: A retrospective analysis of 200 patients from a single Chinese medical institute [J].
Wang, Lei ;
Lao, I. Weng ;
Yu, Lin ;
Wang, Jian .
ONCOLOGY LETTERS, 2017, 14 (05) :5370-5378
[88]   Targeting veGF/veGFR to Modulate Antitumor immunity [J].
Yang, Ju ;
Yan, Jing ;
Liu, Baorui .
FRONTIERS IN IMMUNOLOGY, 2018, 9
[89]   Prognosis and treatment of non-metastatic primary and secondary breast angiosarcoma: a comparative study [J].
Yin, Ming ;
Wang, Wenge ;
Drabick, Joseph J. ;
Harold, Harvey A. .
BMC CANCER, 2017, 17
[90]   First-line anthracycline-based chemotherapy for angiosarcoma and other soft tissue sarcoma subtypes: Pooled analysis of eleven European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group trials [J].
Young, R. J. ;
Natukunda, A. ;
Litiere, S. ;
Woll, P. J. ;
Wardelmann, E. ;
van der Graaf, W. T. A. .
EUROPEAN JOURNAL OF CANCER, 2014, 50 (18) :3178-3186
12345678910