Angiosarcoma: a review of diagnosis and current treatment

被引：14

作者：

Cao, Jun ^{[1
]}

Wang, Jiale ^{[2
]}

He, Chiyu ^{[2
]}

Fang, Meiyu ^{[1
]}

机构：

[1] Univ Chinese Acad Sci, Dept Comprehens Med Oncol, Key Lab Head & Neck Canc Translat Res Zhejiang Pr, Canc Hosp,Zhejiang Canc Hosp, Hangzhou, Zhejiang, Peoples R China

[2] Zhejiang Chinese Med Univ, Clin Med Coll 2, Hangzhou, Zhejiang, Peoples R China

来源：

AMERICAN JOURNAL OF CANCER RESEARCH | 2019年 / 9卷 / 11期

关键词：

Angiosarcoma; aetiology; diagnosis; prognostic factors; chemotherapy; targeted; RADIATION-INDUCED ANGIOSARCOMA; CONTRAST-ENHANCED ULTRASOUND; CUTANEOUS ANGIOSARCOMA; CARDIAC ANGIOSARCOMA; GENE AMPLIFICATION; PROGNOSTIC-FACTORS; MYC; PACLITAXEL; OUTCOMES; THERAPY;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Angiosarcoma is a highly malignancy of endothelial tumor and represents 1-2% of all soft tissue sarcomas in humans. The aetiology of angiosarcoma is not clear but there are definite risk factors including chronic lymphoedema, history of radiation, environmental carcinogens and certain familial syndromes. Ultrasound, CT and MR are diagnostic tools, but final diagnosis requires pathological and immunohistochemical confirmation. The conventional options of treatment include surgery, radiotherapy and chemotherapy. Targeted medicines and immunotherapy have been studied as promising treatment of angiosarcoma. The goal of this review is to summarize the current data regarding of angiosarcoma and its clinical presentation and management, providing a useful clinical tool to explore the optimal treatment.

引用

页码：2303 / 2313

页数：11

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