Quantitative Characterization of Concentrated Cell Pellet Biophantoms using Statistical Models for the Ultrasound Echo Envelope

被引:10
作者
Cristea, A. [1 ,2 ,3 ,4 ,5 ]
Franceschini, E. [6 ]
Lin, F. [1 ,2 ,3 ,4 ,5 ]
Mamou, J. [7 ]
Cachard, C. [1 ,2 ,3 ,4 ,5 ]
Basset, O. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Lyon, CREATIS, Villeurbanne, France
[2] CNRS, UMR5220, F-75700 Paris, France
[3] INSERM, U1044, F-75654 Paris 13, France
[4] INSA Lyon, Villeurbanne, France
[5] Univ Lyon 1, F-69622 Villeurbanne, France
[6] Aix Marseille Univ, Cent Marseille, CNRS UPR 7051, LMA, F-13402 Marseille 20, France
[7] Riverside Res, FL Lizzi Ctr Biomed Engn, New York, NY USA
来源
Proceedings of the 2015 ICU International Congress on Ultrasonics | 2015年 / 70卷
关键词
Tissue Characterization; Nakagami distribution; Homodyned-K distribution; cell pellet biophantoms; concentrated media;
D O I
10.1016/j.phpro.2015.08.233
中图分类号
O59 [应用物理学];
学科分类号
摘要
Statistical analysis is performed on the envelopes of ultrasonic backscattered signals from concentrated human leukemia cell pellet biophantoms. Two statistical distributions (Nakagami and Homodyned-K) are used to assess scatterer concentration. Seven concentrations ranging from 0.006 to 0.30 (corresponding to 3 to 250 scatterers per resolution cell at 25 and 35MHz) are considered. The values of the Nakagami parameter m increase with the number of scatterers per resolution cell but plateaus around 1 for concentrations greater than 0.03, while the Homodyned-K parameter alpha continued to increase and does not plateau, even if the estimation is less precise. (C) 2015 The Authors. Published by Elsevier B.V.
引用
收藏
页码:1091 / 1095
页数:5
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