Risk factors of the efficacy of hepatitis B vaccine in health-care workers

被引：1

作者：

Salehi, Hassan ^{[1
]}

Salehi, Marzieh ^{[2
]}

Kalbasi, Nader ^{[3
]}

Salehi, Maryam ^{[4
]}

Sharifian, Jalil ^{[5
]}

Salehi, Mohammad Mahdi ^{[4
]}

机构：

[1] Isfahan Univ Med Sci, Infect Dis & Trop Med Res Ctr, Esfahan, Iran

[2] Isfahan Univ Med Sci, Sch Med, Dept Infect Dis, Esfahan, Iran

[3] Khoraskan Univ, Fac Dent, Dept Oral & Facial Pathol, Esfahan, Iran

[4] Isfahan Univ Med Sci, Sch Dent, Dent Student Res Ctr, Esfahan, Iran

[5] Shahid Beheshti Univ Med Sci, Sch Dent, Dept Oral Surg, Tehran, Iran

来源：

JOURNAL OF RESEARCH IN MEDICAL SCIENCES | 2020年 / 25卷

关键词：

Health-care workers; hepatitis B; vaccine efficacy; IMMUNOGENICITY;

D O I：

10.4103/jrms.JRMS_1054_18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Conventional hepatitis B virus vaccination fails to achieve efficient protection in about 5%-10% of the world population. Different factors influence the immunogenicity of hepatitis B vaccine. This study aimed to evaluate these factors in health-care workers. Materials and Methods: This was a descriptive study which was implemented among 140 of medical and dental staff working as health-care workers who were low responder after vaccination entered the study. Results: Age (>40 years), weight (body mass index >25), immunodeficiency diseases, (primary immune deficiency and immunosuppressant drugs), diabetes mellitus, and smoking were the important factors. Conclusion: In the high-risk group of hepatitis B disease, the risk factors of immunogenicity must be evaluated at vaccination and check titers of antibody after vaccination.

引用

页数：3

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