A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity

被引:120
作者
Zhang, Hongxing [1 ]
Liu, Jing [1 ]
Sun, Yuan-Qiang [1 ]
Huo, Yingying [1 ]
Li, Yaohua [1 ]
Liu, Weizhi [1 ]
Wu, Xiao [1 ]
Zhu, Nishu [1 ]
Shi, Yawei [2 ]
Guo, Wei [1 ]
机构
[1] Shanxi Univ, Sch Chem & Chem Engn, Taiyuan 030006, Peoples R China
[2] Shanxi Univ, Inst Biotechnol, Taiyuan 030006, Peoples R China
关键词
NITRIC-OXIDE; OXIDATION; MACROPHAGES; SUPEROXIDE; DIACETATE; OXYGEN;
D O I
10.1039/c4cc09122a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A mitochondria-targetable fluorescence probe, methyl(4-hydroxyphenyl) amino-substituted pyronin (1), was exploited, which could highly selectively sense peroxynitrite (ONOO-) within seconds.
引用
收藏
页码:2721 / 2724
页数:4
相关论文
共 38 条
[1]   Stressor-Induced Increase in Microbicidal Activity of Splenic Macrophages Is Dependent upon Peroxynitrite Production [J].
Allen, Rebecca G. ;
Lafuse, William P. ;
Powell, Nicole D. ;
Marketon, Jeanette I. Webster ;
Stiner-Jones, La'Tonia M. ;
Sheridan, John F. ;
Bailey, Michael T. .
INFECTION AND IMMUNITY, 2012, 80 (10) :3429-3437
[2]   The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord [J].
Ashki, N. ;
Hayes, K. C. ;
Bao, F. .
NEUROSCIENCE, 2008, 156 (01) :107-117
[3]   Genetically Encoded Fluorescent Probe for the Selective Detection of Peroxynitrite [J].
Chen, Zhi-jie ;
Ren, Wei ;
Wright, Quintin E. ;
Ai, Hui-wang .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (40) :14940-14943
[4]   Cooperation between reactive oxygen and nitrogen intermediates in killing of Rhodococcus equi by activated macrophages [J].
Darrah, PA ;
Hondalus, MK ;
Chen, QP ;
Ischiropoulos, H ;
Mosser, DM .
INFECTION AND IMMUNITY, 2000, 68 (06) :3587-3593
[5]   Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals [J].
Ferrer-Sueta, Gerardo ;
Radi, Rafael .
ACS CHEMICAL BIOLOGY, 2009, 4 (03) :161-177
[6]   Dihydrofluorescein diacetate is superior for detecting intracellular oxidants:: Comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123 [J].
Hempel, SL ;
Buettner, GR ;
O'Malley, YQ ;
Wessels, DA ;
Flaherty, DM .
FREE RADICAL BIOLOGY AND MEDICINE, 1999, 27 (1-2) :146-159
[7]   Targeting mitochondria [J].
Hoye, Adam T. ;
Davoren, Jennifer E. ;
Wipf, Peter ;
Fink, Mitchell P. ;
Kagan, Valerian E. .
ACCOUNTS OF CHEMICAL RESEARCH, 2008, 41 (01) :87-97
[8]  
Johnson I., 2010, Molecular Probes Handbook, A guide to fluorescent probes and labeling technologies: Molecular Probes, V11th
[9]   A boronate-based fluorescent probe for the selective detection of cellular peroxynitrite [J].
Kim, Jiyoung ;
Park, Jeesook ;
Lee, Hawon ;
Choi, Yongdoo ;
Kim, Youngmi .
CHEMICAL COMMUNICATIONS, 2014, 50 (66) :9353-9356
[10]   Oxidation of 2',7'-dichlorofluorescin by peroxynitrite [J].
Kooy, NW ;
Royall, JA ;
Ischiropoulos, H .
FREE RADICAL RESEARCH, 1997, 27 (03) :245-254