DETERMINATION OF TRACE ELEMENTS IN HAIR ANALYSIS USING ICP-MASS SPECTROMETRY

被引:0
作者
Udristioiu, Aurelian [1 ]
Giubelan, Alexandru [1 ]
Nica-Badea, Delia [2 ]
机构
[1] Titu Maiorescu Univ Bucharest, Fac Med, Bucharest, Romania
[2] Constantin Brancusi Univ, Fac Med & Behav Sci, Targu Jiu, Romania
来源
PHARMACOPHORE | 2021年 / 12卷 / 03期
关键词
Hair analysis; ICP-MS; Nutritive metals; Toxic metals;
D O I
10.51847/Ft7qx3VOb5
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Determining the trace element levels in the human hair is a significant analytical technique, a screening element in the evaluation of possible deficiencies, excesses, and/or biochemical imbalances in all bodies of these microelements. In this work of research, by an inductively coupled plasma- mass spectrometry (ICP-MS) analyzer, the authors have proposed the discovery of toxic trace elements (Al, Pb, Hg) and levels principal mineral elements (Ca, Mg, Cu, Zn) from the human body on healthy individuals with a good nutritional status. The study was performed on a sample of 75 adult women (30-35 years old) from different regions of the country, by taking 100 mg of hair from the base of the scalp with a length of 3 cm, for analysis and evaluation of trace elements. Twelve patients (16%) had high mean values of intracellular Mg (1.2 mmol / L), high Ca values (0.72 mmol / L), but low mean Ca / Mg ratios, (0.58). In addition, six patients (8%) had low mean values of Mg (0.004 mmol / L) and Ca (0.04 mmol / L) but a high Ca / Mg ratio. At the moment of analysis, all individuals did not have acute or severe intoxication signs with heavy metals. The environmental lifestyle of analyzed individuals, from various areas of the country, was observed in their hair cells, by present levels of trace elements. Copyright (C) 2013 - All Rights Reserved - Pharmacophore
引用
收藏
页码:54 / 59
页数:6
相关论文
共 24 条
  • [1] Afridi H, 2008, SCI TOTAL ENVIRON, V389, P270
  • [2] Al-Muzafar HM, 2008, BIOL TRACE ELEM RES, V122, P1
  • [3] Concentrations of heavy metals in hair as indicators of environmental pollution
    Baran, A.
    Wieczorek, J.
    [J]. PROCEEDINGS OF THE 16TH INTERNATIONAL CONFERENCE ON HEAVY METALS IN THE ENVIRONMENT, 2013, 1
  • [4] Blicharska E., 2014, J ANAL BIOANAL TECH, V5, P207, DOI [10.4172/2155-9872.1000207, DOI 10.4172/2155-9872.1000207]
  • [5] Inter-element interactions in human hair
    Chojnacka, K
    Górecka, H
    Chojnacki, A
    Górecki, H
    [J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2005, 20 (02) : 368 - 374
  • [6] Czerny Boguslaw, 2014, ScientificWorldJournal, V2014, P953181, DOI 10.1155/2014/953181
  • [7] Faller EM, 2020, ARCH PHARM PRACT, V11, P40
  • [8] Gaza M.A., 2017, Int J Pharm Clin Res, V9, P710
  • [9] Ghorbani A., 2013, INT RES J APPL BASIC, V4, P3675
  • [10] Hanawi SA, 2020, INT J PHARM RES ALLI, V9, P1