Estimation of the number of virus particles transmitted by an insect vector

被引：124
作者：
Moury, Benoit [1 ]
Fabre, Frederic
Senoussi, Rachid
机构：
[1] INRA, UR407, F-84143 Montfavet, France
[2] INRA, UR546, Biostat & Processus Spatiaux, F-84914 Montfavet, France
[3] Univ Calif Irvine, Irvine, CA USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2007年 / 104卷 / 45期
关键词：
aphid; genetic drift; population bottleneck; potyvirus; nonpersistent virus;
D O I：
10.1073/pnas.0702739104
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Plant viruses are submitted to narrow population bottlenecks both during infection of their hosts and during horizontal transmission between host individuals. The size of bottlenecks exerted on virus populations during plant invasion has been estimated in a few pathosystems but is not addressed yet for horizontal transmission. Using competition for aphid transmission between two Potato virus Y variants, one of them being noninfectious but equally transmissible, we obtained estimates of the size of bottlenecks exerted on an insect-borne virus during its horizontal transmission. We found that an aphid transmitted on average 0.5-3.2 virus particles, which is extremely low compared with the census viral population into a plant. Such narrow bottlenecks emphasize the strength of stochastic events acting on virus populations, and we illustrate, in modeling virus emergence, why estimating this parameter is important.
引用
收藏
页码：17891 / 17896
页数：6
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