Flavonoids from Anoectochilus annamensis and their Anti-inflammatory Activity

被引：1
作者：
Tran Minh Hoi [1 ]
Tran Van Thai [2 ]
Chu Thi Thu Ha [1 ]
Ha Thi Van Anh [1 ]
Phan Xuan Binh Minh [3 ]
Nguyen Tien Dat [2 ]
机构：
[1] VAST, IEBR, 18-Hoang Quoc Viet, Hanoi, Vietnam
[2] VAST, Inst Marine Biochem IMBC, Dept Bioact Prod, 18-Hoang Quoc Viet, Hanoi, Vietnam
[3] Natl Ctr Technol Progress, Ctr Expt Biol, C6 Thanh Xuan Bac, Hanoi, Vietnam
来源：
NATURAL PRODUCT COMMUNICATIONS | 2016年 / 11卷 / 05期
关键词：
Anoectochilus annamensis; Annamflavone; Flavone; Anti-inflammatory; CELLS;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new flavonol diglycoside, 4',5-dihydroxy-3,3',7-trimethoxyflavone 4'-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (1), and two known compounds (2-3) were isolated from the methanolic extract of Anoectochilus annamensis Aver. aerial parts. The effects were evaluated of all isolated compounds (1-3) on LPS-induced production of the inflammatory mediator nitric oxide (NO) by RAW264.7 cells. 4',5-Dihydroxy-3,3',7-trimethoxyflavone (2) was the most active while the addition of a rutinoside at C-4' (compound 1) decreased the inhibitory activity. This is the first report on the chemical composition and biological activity of A. annamensis.
引用
收藏
页码：613 / 614
页数：2
相关论文
共 50 条
[21]   Flavonoids, anti-inflammatory activity and cytotoxicity of Macfadyena unguis-cati L. [J].
Aboutabl, E. A. ;
Hashem, F. A. ;
Sleem, A. A. ;
Maamoon, A. A. .
AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 2008, 5 (01) :18-26
[22]   Distribution, Accumulation of Sabia parviflora Active Components, and Anti-inflammatory Activity of Flavonoids Monomer [J].
Zhou, Mingyang ;
Chen, Jingzhong ;
Xu, Zhanchi ;
Pan, Guoji ;
Wang, Jian ;
Qian, Haibing ;
Sun, Qingwen .
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2025,
[23]   Antinociceptive, anti-inflammatory, and antioxidant properties of flavonoids extracted from Cinnamomum longepaniculatum [J].
Zhou, Ling ;
Huang, Yongyuan ;
Wei, Qin ;
Wu, Fang ;
Yin, Zhongqiong .
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2022, 15 (10) :345-352
[24]   A new labdane diterpenoid with anti-inflammatory activity from Thuja orientalis [J].
Kim, Tae-Hee ;
Li, Hua ;
Wu, Qian ;
Lee, Hwa Jin ;
Ryu, Jae-Ha .
JOURNAL OF ETHNOPHARMACOLOGY, 2013, 146 (03) :760-767
[25]   Glucans from the Caripia montagnei mushroom present anti-inflammatory activity [J].
Queiroz, Lissandra S. ;
Nascimento, Marilia S. ;
Cruz, Ana K. M. ;
Castro, Allisson J. G. ;
Moura, Maria de Fatima V. ;
Baseia, Iuri G. ;
Araujo, Renata M. ;
Benevides, Norma M. B. ;
Agnez Lima, Lucymara F. ;
Leite, Edda Lisboa .
INTERNATIONAL IMMUNOPHARMACOLOGY, 2010, 10 (01) :34-42
[26]   Alkaloids from aerial parts of Houttuynia cordata and their anti-inflammatory activity [J].
Ahn, Jongmin ;
Chae, Hee-Sung ;
Chin, Young-Won ;
Kim, Jinwoong .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (12) :2807-2811
[27]   Flavonoids and triterpenes from Combretum fragrans with anti-inflammatory, antioxidant and antidiabetic potential [J].
Dawe, Amadou ;
Mbiantcha, Marius ;
Yakai, Fawai ;
Jabeen, Almas ;
Ali, Muhammad Shaiq ;
Lateef, Mehreen ;
Ngadjui, Bonaventure Tchaleu .
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, 2018, 73 (5-6) :211-219
[28]   Flavonoids From the Aerial Parts of Sophora tonkinensis and Their Potential Anti-Inflammatory Activities [J].
Yang, Qing-Qing ;
Yang, Yan-Fei ;
Chen, Xuan-Qin ;
Li, Rong-Tao ;
Zhang, Zhi-Jun .
CHEMISTRY & BIODIVERSITY, 2024, 21 (06)
[29]   Antioxidant and Anti-Inflammatory Activities of Six Flavonoids from Smilax glabra Roxb [J].
Zhao, Xinyu ;
Chen, Ruyi ;
Shi, Yueyue ;
Zhang, Xiaoxi ;
Tian, Chongmei ;
Xia, Daozong .
MOLECULES, 2020, 25 (22)
[30]   Anti-oxidative and Anti-inflammatory Effects of Flavonoids from the Silk of Zea mays Linn [J].
Oh, M. H. ;
Choe, K. I. ;
Cho, S. H. ;
Jeong, M. S. ;
Myung, S. C. ;
Seo, S. J. ;
Choi, S. E. ;
Lee, M. W. .
ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (08) :4293-4297
12345