Flavonoids from Anoectochilus annamensis and their Anti-inflammatory Activity

被引：0
|
作者：
Tran Minh Hoi [1 ]
Tran Van Thai [2 ]
Chu Thi Thu Ha [1 ]
Ha Thi Van Anh [1 ]
Phan Xuan Binh Minh [3 ]
Nguyen Tien Dat [2 ]
机构：
[1] VAST, IEBR, 18-Hoang Quoc Viet, Hanoi, Vietnam
[2] VAST, Inst Marine Biochem IMBC, Dept Bioact Prod, 18-Hoang Quoc Viet, Hanoi, Vietnam
[3] Natl Ctr Technol Progress, Ctr Expt Biol, C6 Thanh Xuan Bac, Hanoi, Vietnam
来源：
NATURAL PRODUCT COMMUNICATIONS | 2016年 / 11卷 / 05期
关键词：
Anoectochilus annamensis; Annamflavone; Flavone; Anti-inflammatory; CELLS;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new flavonol diglycoside, 4',5-dihydroxy-3,3',7-trimethoxyflavone 4'-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (1), and two known compounds (2-3) were isolated from the methanolic extract of Anoectochilus annamensis Aver. aerial parts. The effects were evaluated of all isolated compounds (1-3) on LPS-induced production of the inflammatory mediator nitric oxide (NO) by RAW264.7 cells. 4',5-Dihydroxy-3,3',7-trimethoxyflavone (2) was the most active while the addition of a rutinoside at C-4' (compound 1) decreased the inhibitory activity. This is the first report on the chemical composition and biological activity of A. annamensis.
引用
收藏
页码：613 / 614
页数：2
相关论文
共 50 条
  • [1] Anti-inflammatory activity of flavonoids from Eupatorium arnottianum
    Clavin, M.
    Gorzalczany, S.
    Macho, A.
    Munoz, E.
    Ferraro, G.
    Acevedo, C.
    Martino, V.
    JOURNAL OF ETHNOPHARMACOLOGY, 2007, 112 (03) : 585 - 589
  • [2] Anti-inflammatory activity of flavonoids from Chrozophora tinctoria
    Abdallah, Hossam M.
    Almowallad, Fahad M.
    Esmat, Ahmed
    Shehata, Ibrahim A.
    Abdel-Sattar, Essam A.
    PHYTOCHEMISTRY LETTERS, 2015, 13 : 74 - 80
  • [3] Anti-inflammatory activity of flavonoids from Populus davidiana
    Zhang, XinFeng
    Hung, Tran Manh
    Phuong, Phuong Thien
    Ngoc, Tran Minh
    Min, Byung-Sun
    Song, Kyung-Sik
    Seong, Yeon Hee
    Bae, KiHwan
    ARCHIVES OF PHARMACAL RESEARCH, 2006, 29 (12) : 1102 - 1108
  • [4] Flavonoids from Artemisia copa with anti-inflammatory activity
    Moscatelli, V
    Hnatyszyn, O
    Acevedo, C
    Megías, J
    Alcaraz, MJ
    Ferraro, G
    PLANTA MEDICA, 2006, 72 (01) : 72 - 74
  • [5] Flavonoids from the leaves of Apocynum venetum and their anti-inflammatory activity
    Hong-Min Fu
    Chun-Ling Yin
    Zhi-Yong Shen
    Ming-Hua Yang
    JOURNAL OF CHEMICAL RESEARCH, 2022, 46 (01)
  • [6] Anti-inflammatory activity of flavonoids from Cayaponia tayuya roots
    Aquila, Silvia
    Giner, Rosa M.
    Recio, Maria C.
    Spegazzini, Etile D.
    Luis Rios, Jose
    JOURNAL OF ETHNOPHARMACOLOGY, 2009, 121 (02) : 333 - 337
  • [7] Anti-inflammatory activity of flavonoids fromPopulus davidiana
    XinFeng Zhang
    Tran Manh Hung
    Phuong Thien Phuong
    Tran Minh Ngoc
    Byung-Sun Min
    Kyung-Sik Song
    Yeon Hee Seong
    KiHwan Bae
    Archives of Pharmacal Research, 2006, 29 : 1102 - 1108
  • [8] Anti-inflammatory activity of natural dietary flavonoids
    Pan, Min-Hsiung
    Lai, Ching-Shu
    Ho, Chi-Tang
    FOOD & FUNCTION, 2010, 1 (01) : 15 - 31
  • [9] Triterpenoid saponins and flavonoids from licorice residues with anti-inflammatory activity
    Bai, Ming
    Yao, Guo-Bong
    Ren, Qiang
    Li, Qin
    Liu, Qing-Bo
    Zhang, Yan
    Wang, Xiao-Bo
    Huang, Xiao-Xiao
    Song, Shao-Jiang
    INDUSTRIAL CROPS AND PRODUCTS, 2018, 125 : 50 - 58
  • [10] Flavonoids and biphenylneolignans with anti-inflammatory activity from the stems of Millettia griffithii
    Tang, Huan
    Pei, He-Ying
    Wang, Tai-Jin
    Chen, Kai
    Wu, Bo
    Yang, Qiu-Nan
    Zhang, Qiang
    Yang, Jian-Hong
    Wang, Xiao-Yan
    Tang, Ming-Hai
    Peng, Ai-Hua
    Ye, Hao-Yu
    Chen, Li-Juan
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (18) : 4417 - 4422
12345