Stereocontrolled Synthesis of Planar Chiral Carba-Paracyclophanes via Modular Assembly

被引：9
作者：
Jung, Sunna [1 ]
Kitajima, Yoko [1 ]
Ueda, Yasuyuki [1 ]
Suzuki, Keisuke [1 ]
Ohmori, Ken [1 ]
机构：
[1] Tokyo Inst Technol, Dept Chem, Meguro Ku, 2-12-1 O Okayama, Tokyo 1528551, Japan
来源：
SYNLETT | 2016年 / 27卷 / 10期
关键词：
cyclophanes; paracyclophanes; planar chirality; atropisomerism; sulfoxides; hydrogen bond; metathesis; RING-CLOSING METATHESIS; ENANTIOSELECTIVE SYNTHESIS; MACROCYCLIZATION; RESOLUTION; EFFICIENT;
D O I：
10.1055/s-0035-1561937
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Described herein is a flexible modular approach to planar chiral carba-paracyclophanes via the stepwise assembly of two distinct side arms and the aromatic core followed by ring-closing olefin metathesis. Planar chirality is induced by one chiral sulfinyl group by forming a hydrogen bond to the phenol in the aromatic unit.
引用
收藏
页码：1521 / 1526
页数：6
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